Supporting data and materials for "Large-scale analysis of evolutionary histories of phosphorylation motifs in the human genome".
Dataset type: Proteomic
Data released on April 09, 2015
Yoshizaki H; Okuda S (2015): Supporting data and materials for "Large-scale analysis of evolutionary histories of phosphorylation motifs in the human genome". GigaScience Database. https://doi.org/10.5524/100136
Protein phosphorylation is a post-translational modification that is essential for a wide range of eukaryotic physiological processes, such as transcription, cytoskeletal regulation, cell metabolism, and signal transduction. In this study, we provide data for the assessments of functional phosphorylation signaling using comparative proteome analysis of phosphorylation motifs. Data for 93,101 phosphosites and 1,003,756 potential phosphosites are described and provide an overview of evolutionary patterns of phosphomotif acquisition and indicate dependence on motif structures. By using these data, we described interaction networks of phosphoproteins, identified kinase substrates associated with phosphoproteins, and performed gene ontology enrichment analyses.
Additional details
Read the peer-reviewed publication(s):
- Yoshizaki, H., & Okuda, S. (2015). Large-scale analysis of the evolutionary histories of phosphorylation motifs in the human genome. GigaScience, 4(1). https://doi.org/10.1186/s13742-015-0057-6
Additional information:
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Table SettingsFile Name | Description | Sample ID | Data Type | File Format | Size | Release Date | File Attributes | Download |
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Readme | TEXT | 1.42 kB | 2015-03-19 | MD5 checksum: 04d35ddb2183942978aff413125fb9bc |
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93,101 known phosphosites in the human genome | Tabular data | EXCEL | 2.73 MB | 2015-03-19 | ||||
1,003,756 potential phosphosites in the human genome | Text | TEXT | 352.45 MB | 2015-03-19 | MD5 checksum: 45cb4971ec6aebcdc203842cd5337560 |
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cytoscape interactions network of proteins with known phospho-motifs | Other | Cytoscape | 6.92 MB | 2015-03-19 | MD5 checksum: adf2ce87d057aef2cd8a1016f9cd6aa6 |
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Sequence logo images for phosphomotifs that were defined in the present study and bar plots for conservation of each phosphomotif. | Image | GZIP | 51.08 MB | 2015-01-30 | MD5 checksum: ec686ba3ae224612bbd83599f50d0e27 |
Date | Action |
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March 31, 2015 | Additional file Images added |
March 31, 2015 | Additional file Images added |
May 8, 2015 | Manuscript Link added : 10.1186/s13742-015-0057-6 |