Perturbation of epidermal growth factor receptor complex formation and Ras signalling in cells harbouring the hepatitis C virus subgenomic replicon

References

1. Balasubramanian A., Ganju R. K., Groopman J. E. 2003; Hepatitis C virus and HIV envelope proteins collaboratively mediate interleukin-8 secretion through activation of p38 MAP kinase and SHP2 in hepatocytes. J Biol Chem 278:35755–35766 [CrossRef]
   [Google Scholar]
2. Chang G.-C., Hsu S.-L., Tsai J.-R., Liang F.-P., Lin S.-Y., Sheu G.-T., Chen C.-Y. 2004; Molecular mechanisms of ZD1839-induced G1-cell cycle arrest and apoptosis in human lung adenocarcinoma A549 cells. Biochem Pharmacol 68:1453–1464 [CrossRef]
   [Google Scholar]
3. Chen C.-J., Sugiyama K., Kubo H., Huang C., Makino S. 2004; Murine coronavirus nonstructural protein p28 arrests cell cycle in G₀/G₁ phase. J Virol 78:10410–10419 [CrossRef]
   [Google Scholar]
4. de Rooij J., Bos J. L. 1997; Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras. Oncogene 14:623–625 [CrossRef]
   [Google Scholar]
5. Duong F. H., Filipowicz M., Tripodi M., La Monica N., Heim M. H. 2004; Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A. Gastroenterology 126:263–277 [CrossRef]
   [Google Scholar]
6. Erhardt A., Hassan M., Heintges T., Häussinger D. 2002; Hepatitis C virus core protein induces cell proliferation and activates ERK, JNK, and p38 MAP kinases together with the MAP kinase phosphatase MKP-1 in a HepG2 Tet-Off cell line. Virology 292:272–284 [CrossRef]
   [Google Scholar]
7. Fan Y.-X., Wong L., Deb T. B., Johnson G. R. 2004; Ligand regulates epidermal growth factor receptor kinase specificity: activation increases preference for GAB1 and SHC versus autophosphorylation sites. J Biol Chem 279:38143–38150 [CrossRef]
   [Google Scholar]
8. Fukuda K., Tsuchihara K., Hijikata M., Nishiguchi S., Kuroki T., Shimotohno K. 2001; Hepatitis C virus core protein enhances the activation of the transcription factor, Elk1, in response to mitogenic stimuli. Hepatology 33:159–165 [CrossRef]
   [Google Scholar]
9. Georgopoulou U., Caravokiri K., Mavromara P. 2003; Suppression of the ERK1/2 signaling pathway from HCV NS5A protein expressed by herpes simplex recombinant viruses. Arch Virol 148:237–251 [CrossRef]
   [Google Scholar]
10. Hanafusa H., Torii S., Yasunaga T., Nishida E. 2002; Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway. Nat Cell Biol 4:850–858 [CrossRef]
    [Google Scholar]
11. Izumiya Y., Lin S.-F., Ellison T. J., Levy A. M., Mayeur G. L., Izumiya C., Kung H.-J. 2003; Cell cycle regulation by Kaposi's sarcoma-associated herpesvirus K-bZIP: direct interaction with cyclin-CDK2 and induction of G₁ growth arrest. J Virol 77:9652–9661 [CrossRef]
    [Google Scholar]
12. Kar-Roy A., Korkaya H., Oberoi R., Lal S. K., Jameel S. 2004; The hepatitis E virus open reading frame 3 protein activates ERK through binding and inhibition of the MAPK phosphatase. J Biol Chem 279:28345–28357 [CrossRef]
    [Google Scholar]
13. Krieger N., Lohmann V., Bartenschlager R. 2001; Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations. J Virol 75:4614–4624 [CrossRef]
    [Google Scholar]
14. Macdonald A., Harris M. 2004; Hepatitis C virus NS5A: tales of a promiscuous protein. J Gen Virol 85:2485–2502 [CrossRef]
    [Google Scholar]
15. Macdonald A., Crowder K., Street A., McCormick C., Saksela K., Harris M. 2003; The hepatitis C virus non-structural NS5A protein inhibits activating protein-1 function by perturbing Ras-ERK pathway signaling. J Biol Chem 278:17775–17784 [CrossRef]
    [Google Scholar]
16. Macdonald A., Crowder K., Street A., McCormick C., Harris M. 2004; The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity. J Gen Virol 85:721–729 [CrossRef]
    [Google Scholar]
17. Macdonald A., Mazaleyrat S., McCormick C. 7 other authors 2005; Further studies on hepatitis C virus NS5A–SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling. J Gen Virol 86:1035–1044 [CrossRef]
    [Google Scholar]
18. Marshall A., Rushbrook S., Davies S. E., Morris L. S., Scott I. S., Vowler S. L., Coleman N., Alexander G. 2005; Relation between hepatocyte G1 arrest, impaired hepatic regeneration, and fibrosis in chronic hepatitis C virus infection. Gastroenterology 128:33–42 [CrossRef]
    [Google Scholar]
19. Morita E., Nakashima A., Asao H., Sato H., Sugamura K. 2003; Human parvovirus B19 nonstructural protein (NS1) induces cell cycle arrest at G₁ phase. J Virol 77:2915–2921 [CrossRef]
    [Google Scholar]
20. Okada S., Pessin J. E. 1996; Interactions between Src homology (SH) 2/SH3 adapter proteins and the guanylnucleotide exchange factor SOS are differentially regulated by insulin and epidermal growth factor. J Biol Chem 271:25533–25538 [CrossRef]
    [Google Scholar]
21. Ravichandran K. S. 2001; Signaling via Shc family adapter proteins. Oncogene 20:6322–6330 [CrossRef]
    [Google Scholar]
22. Smith D. B., Johnson K. S. 1988; Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S -transferase. Gene 67:31–40 [CrossRef]
    [Google Scholar]
23. Street A., Macdonald A., Crowder K., Harris M. 2004; The hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade. J Biol Chem 279:12232–12241 [CrossRef]
    [Google Scholar]
24. Talarmin H., Rescan C., Cariou S., Glaise D., Zanninelli G., Bilodeau M., Loyer P., Guguen-Guillouzo C., Baffet G. 1999; The mitogen-activated protein kinase kinase/extracellular signal-regulated kinase cascade activation is a key signalling pathway involved in the regulation of G₁ phase progression in proliferating hepatocytes. Mol Cell Biol 19:6003–6011
    [Google Scholar]
25. Tan S.-L., Nakao H., He Y., Vijaysri S., Neddermann P., Jacobs B. L., Mayer B. J., Katze M. G. 1999; NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling. Proc Natl Acad Sci U S A 96:5533–5538 [CrossRef]
    [Google Scholar]
26. Tari A. M., Lopez-Berestein G. 2001; GRB2: a pivotal protein in signal transduction. Semin Oncol 28:142–147 [CrossRef]
    [Google Scholar]
27. Tiganis T. 2002; Protein tyrosine phosphatases: dephosphorylating the epidermal growth factor receptor. IUBMB Life 53:3–14 [CrossRef]
    [Google Scholar]
28. WHO 1999; Global surveillance and control of hepatitis C. J Viral Hepat 6:35–47 [CrossRef]
    [Google Scholar]