Studies on Recombination in Schizosaccharomyces pombe
This extract was created in the absence of an abstract.
Excerpt
The last few years have made it increasingly clear that genetic recombination may occur not only between different genes but even between different mutational sites of what appears by functional criteria to represent one individual gene (Demerec, 1955) or one “cistron” (Benzer, 1957), but the low recombination frequencies that characterize this type of genetic exchange have considerably hindered an adequate analysis of the mechanisms that are responsible for this intragenic recombination (Winge, 1955; Bonner, 1956; Pontecorvo, 1956). In those few cases in which a tetrad analysis or at least an analysis of half-tetrads has been carried out, the evidence is conflicting. While there have been no difficulties in interpreting this type of recombination in terms of reciprocal crossing over in some cases encountered in Aspergillus (Pritchard, 1955; Roper and Pritchard, 1955), the non-reciprocal exchanges observed in Neurospora (Mitchell, 1955, 1956; Case and Giles, 1958; Case and Giles, this Symposium) and...
