The Gene Ontology Annotation (GOA) Project: Implementation of GO in SWISS-PROT, TrEMBL, and InterPro

  1. Evelyn Camon1,3,4,
  2. Michele Magrane1,3,
  3. Daniel Barrell1,
  4. David Binns1,
  5. Wolfgang Fleischmann1,
  6. Paul Kersey1,
  7. Nicola Mulder1,
  8. Tom Oinn1,
  9. John Maslen1,
  10. Anthony Cox2, and
  11. Rolf Apweiler1
  1. 1EMBL Outstation—European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK; 2Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK

Abstract

Gene Ontology Annotation (GOA) is a project run by the European Bioinformatics Institute (EBI) that aims to provide assignments of terms from the Gene Ontology (GO) resource to gene products in a number of its databases (http://www.ebi.ac.uk/GOA). In the first stage of this project, GO assignments have been applied to a data set representing the complete human proteome by a combination of electronic mappings and manual curation. This vocabulary has also been applied to the nonredundant proteome sets for all other completely sequenced organisms as well as to proteins from a wide range of organisms where the proteome is not yet complete.

Footnotes

  • 3 These authors contributed equally to this work.

  • 4 Corresponding author.

  • E-MAIL camon{at}ebi.ac.uk; FAX +44 0 1223 494 468.

  • Article and publication are at http://www.genome.org/cgi/doi/10.1101/gr.461403. Article published online before print in March 2003.

    • Received May 24, 2002.
    • Accepted December 30, 2002.
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