Control of Development and Transposon Movement by DNA Methylation in Arabidopsis thaliana

  1. T. KAKUTANI,
  2. M. KATO,
  3. T. KINOSHITA, and
  4. A. MIURA
  1. Department of Integrated Genetics, National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan

This extract was created in the absence of an abstract.

Excerpt

In both vertebrates and plants, mutations abolishingDNA methylation induce developmental abnormalities,which often accompany perturbation of transcription (forreview, see Richards 1997; Habu et al. 2001; Li 2002). Aunique feature in plants is that the induced epigeneticchanges are often inherited over multiple generations evenafter introduction into a wild-type background (for review,see Martienssen 1998; Kakutani 2002). This feature has facilitated identification of plant genes controlled by DNAmethylation through conventional genetic linkage analysis.Tissue-specific as well as parent-of-origin-specific transcriptional control by DNA methylation can be studied further using Arabidopsis mutants affecting epigenetic states...

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