- Poster presentation
- Published:
Evaluation of two sedation techniques in a casualty department
Critical Care volume 11, Article number: P422 (2007)
We compare the efficacy, adverse events, and recovery duration of etomidate and propofol for use in procedural sedation in the emergency department (ED). A randomized nonblinded prospective trial of adult patients undergoing procedural sedation for painful procedures in the ED was made. Patients received either propofol or etomidate. Doses, vital signs, nasal end-tidal CO2 (etco2), pulse oximetry, and bispectral electroencephalogram analysis scores were recorded. Subclinical respiratory depression was defined as a change in etco2 greater than 10 mmHg, an oxygen saturation of less than 92% at any time, or an absent etco2 waveform at any time. Clinical events related to respiratory depression, including an increase in supplemental oxygen, the use of a bag-valve-mask apparatus, airway repositioning, or stimulation to induce breathing, were noted. Etomidate and propofol appear equally safe for ED procedural sedation. Etomidate had a lower rate of procedural success and induced myoclonus in 20% of patients (see Table 1).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Moustafa, M., Borai, M. Evaluation of two sedation techniques in a casualty department. Crit Care 11 (Suppl 2), P422 (2007). https://0-doi-org.brum.beds.ac.uk/10.1186/cc5582
Published:
DOI: https://0-doi-org.brum.beds.ac.uk/10.1186/cc5582