Hydrolyzable Tannins, the Active Constituents of Three Greek Cytinus Taxa against Several Tumor Cell Lines

Prokopios MAGIATIS; Harris PRATSINIS; Eleftherios KALPOUTZAKIS; Anastasia KONSTANTINIDOU; Panagiotis DAVARIS; Alexios-Leandros SKALTSOUNIS

doi:10.1248/bpb.24.707

Notes

Hydrolyzable Tannins, the Active Constituents of Three Greek Cytinus Taxa against Several Tumor Cell Lines

Prokopios MAGIATIS, Harris PRATSINIS, Eleftherios KALPOUTZAKIS, Anastasia KONSTANTINIDOU, Panagiotis DAVARIS, Alexios-Leandros SKALTSOUNIS

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Keywords: hydrolyzable tannins, Cytinus ruber, Cytinus hypocistis, Rafflesiaceae, cytotoxicity

JOURNAL FREE ACCESS

2001 Volume 24 Issue 6 Pages 707-709

DOI https://doi.org/10.1248/bpb.24.707

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Abstract

Hydrolyzable tannins were found to be the active cytotoxic constituents of three Greek Cytinus taxa: Cytinus ruber, Cytinus hypocistis subsp. hypocistis and Cytinus hypocistis subsp. orientalis. The cytotoxic activity was evaluated against a broad spectrum of cancer cell lines. The structure of the active compounds was investigated with NMR and electrospray-MS/MS techniques.

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