Paeonins A and B, Lipoxygenase Inhibiting Monoterpene Galactosides from Paeonia emodi

Naheed Riaz; Itrat Anis; Abdul Malik; Zaheer Ahmed; Aziz-ur-rehman; Pir Muhammad; Sarfraz Ahmad Nawaz; Muhammad Iqbal Choudhary

doi:10.1248/cpb.51.252

Regular Articles

Paeonins A and B, Lipoxygenase Inhibiting Monoterpene Galactosides from Paeonia emodi

Naheed Riaz, Itrat Anis, Abdul Malik, Zaheer Ahmed, Aziz-ur-rehman, Pir Muhammad, Sarfraz Ahmad Nawaz, Muhammad Iqbal Choudhary

Author information

Naheed Riaz
International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi
Itrat Anis
International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi
Abdul Malik
International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi
Zaheer Ahmed
International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi
Aziz-ur-rehman
International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi
Pir Muhammad
International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi
Sarfraz Ahmad Nawaz
International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi
Muhammad Iqbal Choudhary
International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi

Keywords: Paeonia emodi, Paeoniaceae, monoterpene, enzyme inhibition

JOURNAL FREE ACCESS

2003 Volume 51 Issue 3 Pages 252-254

DOI https://doi.org/10.1248/cpb.51.252

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Abstract

Paeonins A and B, new monoterpene galactosides have been isolated from the chloroform-soluble fraction of the roots of Paeonia emodi and showed potent lipoxygenase inhibitory activity. The structures of 1 and 2 have been assigned on the basis of spectral analysis including one- and two-dimensional NMR techniques.

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