Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
A New Mast Cell Degranulating Peptide Homologous to Mastoparan in the Venom of Japanese Hornet (Vespa xanthoptera)
YUKO HIRAIMANABU KUWADATADASHI YASUHARAHISANOBU YOSHIDATERUMI NAKAJIMA
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Keywords: mastoparan-X
JOURNAL FREE ACCESS

1979 Volume 27 Issue 8 Pages 1945-1946

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Abstract

The haemolytic factor in the venom of Japanese hornet (Vespa xanthoptera) was identified as the new peptide consisting of the following sequence ; Ile-Asn-Trp-Lys-Gly-Ile-Ala-Ala-Met-Ala-Lys-Lys-Leu-Leu-NH2 The structure is closely related to mastoparan, and the peptide revealed mast cell degranulating activity and released also serotonin from platelets. The peptide was named "Mastoparan-X."

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© The Pharmaceutical Society of Japan
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