Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Removal of Fine Powders from Film Surface. II. Effect of Operating Parameters on the Removal Efficiency
Satoru WatanoTakumi OkamotoTeruo Suzuki
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2002 Volume 50 Issue 9 Pages 1262-1264

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Abstract

In the previous paper, a novel fine particle removal system composed of a corona-discharge neutralizer, a pulse-jet air unit and an image processing system has been developed and applied to the removal of fine particles from film surface. We have calculated the van der Waals and electrostatic forces between particle and film and then reported that the electrostatic force influenced the adhesion characteristics significantly and thus the elimination of electrostatic charge should be necessary for the effective removal of fine particles. In this paper, we have modified the corona-discharge neutralizer for getting much better removal performance. The effect of operating parameters on the removal efficiency was investigated experimentally. The ratio of fine particle remained on the film surface after removal experiment as a function of particle size was measured. It was found that fine particles smaller than 15 μm, which were impossible to remove by other conventional techniques, could be almost completely removed. This method is anticipated to be used in the capsule filling, film packaging and tabletting processes for prevention of stain on lens of video automatic inspection machines, unpredictable movement of electronic devices, and deteriorates of product quality.

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© 2002 The Pharmaceutical Society of Japan
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