Structures of New Erythrinan Alkaloids and Nitric Oxide Production Inhibitors from Erythrina crista-galli

Masaaki Ozawa; Shunsuke Kawamata; Tadahiro Etoh; Masahiko Hayashi; Kanki Komiyama; Akio Kishida; Chiaki Kuroda; Ayumi Ohsaki

doi:10.1248/cpb.58.1119

Notes

Structures of New Erythrinan Alkaloids and Nitric Oxide Production Inhibitors from Erythrina crista-galli

Masaaki Ozawa, Shunsuke Kawamata, Tadahiro Etoh, Masahiko Hayashi, Kanki Komiyama, Akio Kishida, Chiaki Kuroda, Ayumi Ohsaki

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Keywords: Erythrina crista-galli, Leguminosae, alkaloid, nitric oxide production inhibitor

JOURNAL FREE ACCESS

2010 Volume 58 Issue 8 Pages 1119-1122

DOI https://doi.org/10.1248/cpb.58.1119

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Abstract

Two new Erythrinan alkaloids, cristanines A and B (1, 2), were isolated from the bark of Erythrina crista-galli L. together with nine known Erythrinan alkaloids (3—5, 7—12) and an indole alkaloid (13). The structures of the compounds, cristanines A (1) and B (2), were elucidated by spectroscopic methods. Three of the twelve compounds isolated showed significant inhibitory activity on lipopolysaccharide induced nitric oxide (NO) production.

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