Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Two New Verticillane-Type Diterpenoids from the Formosan Soft Coral Cespitularia hypotentaculata
Shi-Yie ChengEn-Hung LinZhi-Hong WenMichael Yen-Nan ChiangChang-Yih Duh
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2010 Volume 58 Issue 6 Pages 848-851

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Abstract

Chemical investigations of the Formosan soft coral Cespitularia hypotentaculata ROXAS led to the isolation of two new verticillane diterpenoids, cespitularins R and S (1, 2), along with seven known compounds (3—9). The structures of these isolated compounds were elucidated on the basis of extensive spectroscopic analysis and by comparison with those of reported in literature. The anti-inflammatory activity using RAW 264.7 macrophages of compounds 1—9 were evaluated in vitro.

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© 2010 The Pharmaceutical Society of Japan
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