Inflammatory Reaction in the Herniated Degenerative Disc Materials in Miniature Dachshunds

Junichiro SHIMIZU; Kyohei MOCHIDA; Yoshiyasu KOBAYASHI; Masahiko KITAMURA; Hiroshi TANAKA; Miori KISHIMOTO; Ki-Ja LEE; Toshiroh IWASAKI; Yoh-Ichi MIYAKE; Masanari NAKAYAMA; Kazutaka YAMADA

doi:10.1292/jvms.09-0221

Internal Medicine

Inflammatory Reaction in the Herniated Degenerative Disc Materials in Miniature Dachshunds

Junichiro SHIMIZU, Kyohei MOCHIDA, Yoshiyasu KOBAYASHI, Masahiko KITAMURA, Hiroshi TANAKA, Miori KISHIMOTO, Ki-Ja LEE, Toshiroh IWASAKI, Yoh-Ichi MIYAKE, Masanari NAKAYAMA, Kazutaka YAMADA

Author information

Junichiro SHIMIZU
Department of Applied Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
Kyohei MOCHIDA
Department of Applied Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
Yoshiyasu KOBAYASHI
Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
Masahiko KITAMURA
Nakayama Veterinary Hospital
Hiroshi TANAKA
Nakayama Veterinary Hospital
Miori KISHIMOTO
Department of Applied Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
Ki-Ja LEE
Department of Applied Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
Toshiroh IWASAKI
Department of Veterinary Internal Medicine, Tokyo University of Agriculture and Technology
Yoh-Ichi MIYAKE
Department of Applied Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
Masanari NAKAYAMA
Department of Applied Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
Nakayama Veterinary Hospital
Kazutaka YAMADA
Department of Applied Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine

Keywords: canine, inflammatory cell, intervertebral disc herniation, phagocytosis, spontaneous regression

JOURNAL FREE ACCESS

2010 Volume 72 Issue 1 Pages 81-84

DOI https://doi.org/10.1292/jvms.09-0221

View "Advance Publication" version (November 13, 2009).

Details

Abstract

Histological and immunohistochemical studies were conducted using herniated intervertebral disc materials obtained surgically from 39 miniature dachshunds. Infiltration of inflammatory cells, such as macrophages, neutrophils, T or B lymphocytes, and multinucleated giant cells, were identified in intervertebral disc materials in 23 cases. Furthermore, proliferations of connective tissue, including neovascularization, were also observed in 17 cases. These results suggest that spontaneous regression of herniated intervertebral disc material could occur in affected dogs.

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