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Affiliations
Tamara Milovanovic
Clinic of Gastroenterology and Hepatology, Clinical Center of Serbia, Belgrade; Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Ivana Pantic
Clinic of Gastroenterology and Hepatology, Clinical Center of Serbia, Belgrade, Serbia
Sanja Dragasevic
Clinic of Gastroenterology and Hepatology, Clinical Center of Serbia, Belgrade; Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Sofija Lugonja
General hospital “Djordje Joanovic”, Department of Internal medicine, Divison of gastroenterology, Zrenjanin, Serbia
Igor Dumic
Mayo Clinic Alix School of Medicine, Rochester, MN, USA; Mayo Clinic Health System, Eau Claire, WI, USA
Mirjana Rajilic-Stojanovic
Faculty of Technology and Metallurgy, University of Belgrade, Belgrade, Serbia
How to Cite
The Interrelationship Among Non-Alcoholic Fatty Liver Disease, Colonic Diverticulosis and Metabolic Syndrome
Abstract
Non-alcoholic fatty liver disease and colonic diverticulosis are widespread, obesity-related diseases. It has
recently become clear that non-alcoholic fatty liver disease is a systemic disease and may play a key role
in metabolic syndrome; therefore, the term metabolic-dysfunction-associated fatty liver disease has been
introduced in the literature. Excess visceral adipose tissue is an important predictor of complications in both
non-alcoholic fatty liver disease and colonic diverticulosis. Current evidence suggests that intestinal dysbiosis
may be involved in the development of both non-alcoholic fatty liver disease and colonic diverticulosis, and
that metabolic syndrome is a consequence rather than a cause of this complex relationship. In this review, our
aim was to assess the current knowledge of the complex interplay between metabolic syndrome, non-alcoholic
fatty liver disease, and colonic diverticulosis.