Abstract

Non-alcoholic fatty liver disease and colonic diverticulosis are widespread, obesity-related diseases. It has
recently become clear that non-alcoholic fatty liver disease is a systemic disease and may play a key role
in metabolic syndrome; therefore, the term metabolic-dysfunction-associated fatty liver disease has been
introduced in the literature. Excess visceral adipose tissue is an important predictor of complications in both
non-alcoholic fatty liver disease and colonic diverticulosis. Current evidence suggests that intestinal dysbiosis
may be involved in the development of both non-alcoholic fatty liver disease and colonic diverticulosis, and
that metabolic syndrome is a consequence rather than a cause of this complex relationship. In this review, our
aim was to assess the current knowledge of the complex interplay between metabolic syndrome, non-alcoholic
fatty liver disease, and colonic diverticulosis.

Keywords

non-alcoholic fatty liver disease, diverticulosis, metabolic syndrome, metabolic-dysfunction- associated fatty liver disease