Attacks by large carnivores on humans can occasionally help to generate significant resistance to carnivore conservation efforts. We have reviewed research addressing concerns for human safety in large carnivore conservation, and have evaluated statements about the frequencies and causes of attacks based on our findings concerning i) existing data on the number of attacks by large carnivores in various parts of the world; ii) information systems documenting details of attacks; and iii) research that provides credible advice on what to do when encountering a large carnivore, to minimize the likelihood of being attacked. We conclude that little information exists for any of these criteria and what is available is often inadequate to determine the frequency of attacks, their causes and how to avoid them. We suggest that information systems, including database(s) on attacks and encounters, should be established for large carnivore conservation efforts, to supply information and to answer future requests for this information.