Cent Eur J Public Health 2018, 26(2):104-110 | DOI: 10.21101/cejph.a5022

Impact of socio-demographic characteristics and long-term complications on quality of life in patients with diabetes mellitus

Miodrag Stojanović1,2, Goran Cvetanović3, Marija Anđelković Apostolović1,2, Dijana Stojanović1, Nataša Rančić1,4
1 University of Niš, Faculty of Medicine Niš, Niš, Serbia
2 Department of Biostatistics, Institute for Public Health, Niš, Serbia
3 General Hospital of Leskovac, Leskovac, Serbia
4 Centre for Control and Prevention of Diseases, Institute of Public Health, Niš, Serbia

Objective: Diabetes mellitus (DM) has been one of the leading chronic diseases worldwide over past decades. The objective of the study was to identify predictors associated with health-related quality of life (HRQOL) in diabetic patients.

Methods: A cross-sectional questionnaire-based study was conducted at the General Hospital of the city of Leskovac, between June and November 2015. The Short Form-36 (SF-36) questionnaire, EuroQol-5D (EQ-5D) and EuroQol-VAS (EQ-VAS) questionnaires were used. Univariate and multivariate linear regression analyses were performed.

Results: The total number of patients was 285, 112 men (39.3%) and 173 women (60.7%), average age 63.92 ± 1.07 years. The results of multiple linear regression of socio-demographic characteristics in relation to dimensions of the quality of life measured by SF-36 and EQ-VAS showed that age, country (rural) life, low level of education, retirement, and poor economic status are predictors of lower quality of life. Our results showed that employment has a significant association with higher Physical Component Score (PCS), Mental Component Score (MCS) and EQ-VAS score, which can be explained with higher incomes, improved economic status and less possibility for the occurrence of depressive mood. Patients without formal education have lower QOL. Univariate multiple regression analysis of the presence of micro- and macrovascular complications of DM showed that angina pectoris, heart failure, diabetic retinopathy, and diabetic nephropathy are the most important factors affecting the quality of life in our population. After including the multivariate model, all tested complications remained statistically significant.

Conclusion: Our results showed that both socioeconomic and chronic complications are relevant factors of HRQOL in type 1 and 2 diabetes mellitus patients. Age, rural lifestyle, retirement, lower level of education and low socioeconomic status, as well as DM complications (angina pectoris, hearth failure, diabetes nephropathy, and diabetes retinopathy) were found to be independent risk factors for the component scores of SF-36 and EQ-VAS score. Taking into consideration the results obtained, health practitioners should be aware not only of the clinical parameters of patients with DM, but also of their educational level and working status.

Keywords: diabetes mellitus, health-related quality of life, complications, SF-36, EuroQol-5D, EuroQol-VAS

Received: December 28, 2016; Revised: May 14, 2018; Accepted: May 14, 2018; Published: June 30, 2018  Show citation

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Stojanović M, Cvetanović G, Anđelković Apostolović M, Stojanović D, Rančić N. Impact of socio-demographic characteristics and long-term complications on quality of life in patients with diabetes mellitus. Cent Eur J Public Health. 2018;26(2):104-110. doi: 10.21101/cejph.a5022. PubMed PMID: 30102498.
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