IN VIVO BLOOD COMPATIBILITY OF REGENERATED SILK FIBROIN
1989 Volume 45 Issue 11 Pages 487-490
Details
1989 Volume 45 Issue 11 Pages 487-490
Blood compatibility of regenerated silk fibroin was ecamined by in vivo blood tests. In vivo tests were made by a method of peripheral vein indelling suture. The coating of sample fibroin on the polyester suture was made by casting either from aqueous or from formic acid solution. The fibroin-coated sutures from aqueous solution were treated with methanolic aqueous solution in order to denature the silk fibroin, and implanted into a jugular and femoral vein of a dog. The results of the test method employed in this work indicate that the regenerated silk fibroin is nonthrombogenic.
