Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Reactive Hemophagocytosis in Systemic Lupus Erythematosus
Kazuo TAKAHASHIShunichi KUMAKURAHiroto ISHIKURAYohko MURAKAWAYasutaka YAMAUCHIShotai KOBAYASHI
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1998 Volume 37 Issue 6 Pages 550-553

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Abstract

A patient with systemic lupus erythematosus (SLE) developed reactive hemophagocytosis. This case did not show any underlying diseases such as infection or malignancy other than SLE itself. The mechanisms inducing hemophagocytosis in SLE seem to be heterogeneous and remain to be elucidated. Although an immune complex-mediated mechanism in cases with acute lupus hemophagocytic syndrome has been proposed, we suggest the possible involvement of IL-1β as the pathogenesis of our case.
(Internal Medicine 37: 550-553, 1998)

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© The Japanese Society of Internal Medicine
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