Long-term Follow-up of Gastric Adenocarcinoma with Chief Cell Differentiation Using Upper Gastrointestinal Tract Endoscopy

Takashi Abe; Takayuki Nagai; Junji Fukunaga; Hitoshi Okawara; Hiroshi Nakashima; Mitsutaka Syutou; Nobuaki Kajimoto; Ryojin Wake; Tsuneo Oyama; Takashi Yao

doi:10.2169/internalmedicine.52.0361

CASE REPORTS

Long-term Follow-up of Gastric Adenocarcinoma with Chief Cell Differentiation Using Upper Gastrointestinal Tract Endoscopy

Takashi Abe, Takayuki Nagai, Junji Fukunaga, Hitoshi Okawara, Hiroshi Nakashima, Mitsutaka Syutou, Nobuaki Kajimoto, Ryojin Wake, Tsuneo Oyama, Takashi Yao

Author information

Takashi Abe
Department of Gastroenterology, Oita Kouseiren Tsurumi Hospital, Japan
Takayuki Nagai
Department of Gastroenterology, Oita Kouseiren Tsurumi Hospital, Japan
Junji Fukunaga
Department of Gastroenterology, Fukunaga Ichoka-geka Hospital, Japan
Hitoshi Okawara
Department of Gastroenterology, Oita Kouseiren Tsurumi Hospital, Japan
Hiroshi Nakashima
Department of Gastroenterology, Oita Kouseiren Tsurumi Hospital, Japan
Mitsutaka Syutou
Department of Gastroenterology, Oita Kouseiren Tsurumi Hospital, Japan
Nobuaki Kajimoto
Department of Gastroenterology, Oita Kouseiren Tsurumi Hospital, Japan
Ryojin Wake
Department of Gastroenterology, Oita Kouseiren Tsurumi Hospital, Japan
Tsuneo Oyama
Department of Gastroenterology, Saku Central Hospital, Japan
Takashi Yao
Department of Human Pathology, Faculty of Medicine, Juntendo University School of Medicine, Japan

Keywords: chief cell differentiation, fundic gland type, gastric cancer, Ki-67

JOURNAL OPEN ACCESS

2013 Volume 52 Issue 14 Pages 1585-1588

DOI https://doi.org/10.2169/internalmedicine.52.0361

Details

Abstract

During upper endoscopic screening, a 71-year-old asymptomatic woman was found to have a small, yellowish, superficial elevated lesion in the upper third of her stomach, without any signs of atrophic mucosa. The patient underwent endoscopic follow-up once a year for approximately five years; however, changes in the tumor were barely detectable. Endoscopic mucosal resection was performed, and a histological examination confirmed the diagnosis of gastric adenocarcinoma with chief cell differentiation (GA-CCD). GA-CCD is rare; therefore, its clinicopathological features remain unknown. This case suggests that only barely detectable endoscopic changes may be observed in GA-CCD during long-term follow-up.

Corresponding author

Register with J-STAGE for free!