An Autopsy Case Report of Malignant Pleural Mesothelioma with Deciduoid Features

Ryota Ushio; Masaki Yamamoto; Yuji Shibata; Hiroshi Ishii; Keisuke Watanabe; Ryohei Takahashi; Takashi Sato; Makoto Kudo; Akio Miyake; Takeshi Kaneko; Yoshiaki Ishigatsubo

doi:10.2169/internalmedicine.54.4940

CASE REPORTS

An Autopsy Case Report of Malignant Pleural Mesothelioma with Deciduoid Features

Ryota Ushio, Masaki Yamamoto, Yuji Shibata, Hiroshi Ishii, Keisuke Watanabe, Ryohei Takahashi, Takashi Sato, Makoto Kudo, Akio Miyake, Takeshi Kaneko, Yoshiaki Ishigatsubo

Author information

Ryota Ushio
Department of Respiratory Medicine, Yokohama City University Hospital, Japan
Masaki Yamamoto
Department of Respiratory Medicine, Yokohama City University Hospital, Japan
Yuji Shibata
Department of Respiratory Medicine, Yokohama City University Hospital, Japan
Hiroshi Ishii
Department of Respiratory Medicine, Yokohama City University Hospital, Japan
Keisuke Watanabe
Department of Respiratory Medicine, Yokohama City University Hospital, Japan
Ryohei Takahashi
Department of Respiratory Medicine, Yokohama City University Hospital, Japan
Takashi Sato
Department of Respiratory Medicine, Yokohama City University Hospital, Japan
Makoto Kudo
Department of Respiratory Medicine, Yokohama City University Hospital, Japan
Akio Miyake
Department of Pathology, Yokohama City University Hospital, Japan
Takeshi Kaneko
Department of Respirology, Yokohama City University Graduate School of Medicine, Japan
Yoshiaki Ishigatsubo
Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Japan

Keywords: mesothelioma, deciduoid, pleura, autopsy

JOURNAL OPEN ACCESS

2015 Volume 54 Issue 22 Pages 2915-2917

DOI https://doi.org/10.2169/internalmedicine.54.4940

Details

Abstract

Deciduoid mesothelioma is a rare variant of epithelioid mesothelioma. We experienced the case of a 73-year-old man with asbestos exposure who was diagnosed with malignant pleural mesothelioma with deciduoid features. He received chemotherapy containing six cycles of cisplatin and pemetrexed and survived for twenty-five months after the diagnosis. At autopsy, the final diagnosis was biphasic pleural mesothelioma. Cells with deciduoid features had mostly disappeared, and spindle cells markedly proliferated. To the best of our knowledge, this is the first autopsy case of malignant pleural mesothelioma with deciduoid features that exhibited a response to chemotherapy.

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