Penicillium marneffei Infection with β-D-glucan Elevation: A Case Report and Literature Review

Yukihiro Yoshimura; Yohei Sakamoto; Kwangyeol Lee; Yuichiro Amano; Natsuo Tachikawa

doi:10.2169/internalmedicine.55.6173

CASE REPORTS

Penicillium marneffei Infection with β-D-glucan Elevation: A Case Report and Literature Review

Yukihiro Yoshimura, Yohei Sakamoto, Kwangyeol Lee, Yuichiro Amano, Natsuo Tachikawa

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Keywords: Penicillium marneffei, HIV, Japan, β-D-glucan

JOURNAL OPEN ACCESS

2016 Volume 55 Issue 17 Pages 2503-2506

DOI https://doi.org/10.2169/internalmedicine.55.6173

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Abstract

We herein report a case of Penicillium marneffei infection (PMI) in a Japanese man who was infected with human immunodeficiency virus-1 (HIV-1), who was diagnosed on the basis of a bone marrow culture and who was effectively treated with itraconazole. Our review of the PMI cases reported in Japan suggests that increased serum (1→3)-β-D-glucan levels are a useful diagnostic tool in cases of suspected PMI.

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