Abstract
Iron oxide nanomaterials are considered promising tools for improved therapeutic efficacy and diagnostic applications in biomedicine. Accordingly, engineered iron oxide nanomaterials are increasingly proposed in biomedicine, and the interdisciplinary researches involving physics, chemistry, biology (nanotechnology) and medicine have led to exciting developments in the last decades. The progresses of the development of magnetic nanoparticles with tailored physico-chemical and surface properties produced a variety of clinically relevant applications, spanning from magnetic resonance imaging (MRI), drug delivery, magnetic hyperthermia, to in vitro diagnostics. Notwithstanding the wellknown conventional synthetic procedures and their wide use, along with recent advances in the synthetic methods open the door to new generations of naked iron oxide nanoparticles possessing peculiar surface chemistries, suitable for other competitive biomedical applications. New abilities to rationally manipulate iron oxides and their physical, chemical, and biological properties, allow the emersion of additional possibilities for designing novel nanomaterials for theranostic applications.
Keywords: Nanoparticles, iron oxide, nanomaterial synthesis, theranostics, colloids, biomedicine.
Current Medicinal Chemistry
Title:New Perspectives on Biomedical Applications of Iron Oxide Nanoparticles
Volume: 25 Issue: 4
Author(s): Massimiliano Magro, Davide Baratella, Emanuela Bonaiuto, Jessica de A. Roger and Fabio Vianello*
Affiliation:
- Department of Comparative Biomedicine and Food Science, University of Padua,Italy
Keywords: Nanoparticles, iron oxide, nanomaterial synthesis, theranostics, colloids, biomedicine.
Abstract: Iron oxide nanomaterials are considered promising tools for improved therapeutic efficacy and diagnostic applications in biomedicine. Accordingly, engineered iron oxide nanomaterials are increasingly proposed in biomedicine, and the interdisciplinary researches involving physics, chemistry, biology (nanotechnology) and medicine have led to exciting developments in the last decades. The progresses of the development of magnetic nanoparticles with tailored physico-chemical and surface properties produced a variety of clinically relevant applications, spanning from magnetic resonance imaging (MRI), drug delivery, magnetic hyperthermia, to in vitro diagnostics. Notwithstanding the wellknown conventional synthetic procedures and their wide use, along with recent advances in the synthetic methods open the door to new generations of naked iron oxide nanoparticles possessing peculiar surface chemistries, suitable for other competitive biomedical applications. New abilities to rationally manipulate iron oxides and their physical, chemical, and biological properties, allow the emersion of additional possibilities for designing novel nanomaterials for theranostic applications.
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Cite this article as:
Magro Massimiliano, Baratella Davide, Bonaiuto Emanuela , de A. Roger Jessica and Vianello Fabio*, New Perspectives on Biomedical Applications of Iron Oxide Nanoparticles, Current Medicinal Chemistry 2018; 25 (4) . https://dx.doi.org/10.2174/0929867324666170616102922
DOI https://dx.doi.org/10.2174/0929867324666170616102922 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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