Abstract
Ladderanes are hydrocarbons consisting of two or more fused cyclobutane rings. These molecules and their derivatives are of fundamental interest to physical organic chemists due to their strain and electronic properties. Recently, the astonishing discovery that some bacterial lipids contain ladderane substructures has revitalized interest in this class of molecules. This review describes the synthesis, reactivity, applications, and biology of ladderanes.
Keywords: Photochemical Polycyclizations, [2]-ladderane, cyclobutane ring, all-trans ladderanes synthesis, Cyclobutane-Containing Natural products
Current Organic Chemistry
Title: They Came From the Deep: Syntheses, Applications, and Biology of Ladderanes
Volume: 10 Issue: 16
Author(s): Dustin H. Nouri and Dean J. Tantillo
Affiliation:
Keywords: Photochemical Polycyclizations, [2]-ladderane, cyclobutane ring, all-trans ladderanes synthesis, Cyclobutane-Containing Natural products
Abstract: Ladderanes are hydrocarbons consisting of two or more fused cyclobutane rings. These molecules and their derivatives are of fundamental interest to physical organic chemists due to their strain and electronic properties. Recently, the astonishing discovery that some bacterial lipids contain ladderane substructures has revitalized interest in this class of molecules. This review describes the synthesis, reactivity, applications, and biology of ladderanes.
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Cite this article as:
Nouri H. Dustin and Tantillo J. Dean, They Came From the Deep: Syntheses, Applications, and Biology of Ladderanes, Current Organic Chemistry 2006; 10 (16) . https://dx.doi.org/10.2174/138527206778742678
DOI https://dx.doi.org/10.2174/138527206778742678 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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