Abstract
The field of bioinformatics has become a major part of the drug discovery pipeline playing a key role in improvement and acceleration of this time and money consuming process. Here we review the application of the informational spectrum method (ISM), a virtual spectroscopy method for structure/function analysis of proteins, in identification of functional protein domains representing candidate therapeutic targets for drugs against human immunodeficiency virus (HIV)-1, anthrax, highly pathogenic influenza virus H5N1 and cardiovascular diseases.
Keywords: Bioinformatics, target, electron-ion interaction potential, informational spectrum method, H5N1, HIV-1, anthrax
Current Protein & Peptide Science
Title: Discovery of New Therapeutic Targets by the Informational Spectrum Method
Volume: 9 Issue: 5
Author(s): Nevena Veljkovic, Sanja Glisic, Jelena Prljic, Vladimir Perovic, Maurizio Botta and Veljko Veljkovic
Affiliation:
Keywords: Bioinformatics, target, electron-ion interaction potential, informational spectrum method, H5N1, HIV-1, anthrax
Abstract: The field of bioinformatics has become a major part of the drug discovery pipeline playing a key role in improvement and acceleration of this time and money consuming process. Here we review the application of the informational spectrum method (ISM), a virtual spectroscopy method for structure/function analysis of proteins, in identification of functional protein domains representing candidate therapeutic targets for drugs against human immunodeficiency virus (HIV)-1, anthrax, highly pathogenic influenza virus H5N1 and cardiovascular diseases.
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Cite this article as:
Veljkovic Nevena, Glisic Sanja, Prljic Jelena, Perovic Vladimir, Botta Maurizio and Veljkovic Veljko, Discovery of New Therapeutic Targets by the Informational Spectrum Method, Current Protein & Peptide Science 2008; 9 (5) . https://dx.doi.org/10.2174/138920308785915245
DOI https://dx.doi.org/10.2174/138920308785915245 |
Print ISSN 1389-2037 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5550 |
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