Abstract
Traumatic brain injury affects over a million Americans annually, but pharmacological therapy remains limited. Current standards of care in acute, subacute and chronic phases of injury are primarily supportive. This review discusses pharmacological strategies and future directions in patient treatment emphasizing pleiotropic agents targeting inflammation, oxidative damage, and glutamate excitotoxicity.
Mini-Reviews in Medicinal Chemistry
Title: Pharmacological Strategies for Neuroprotection in Traumatic Brain Injury
Volume: 8 Issue: 7
Author(s): J. S. Jennings, A. M. Gerber and M. L. Vallano
Affiliation:
Abstract: Traumatic brain injury affects over a million Americans annually, but pharmacological therapy remains limited. Current standards of care in acute, subacute and chronic phases of injury are primarily supportive. This review discusses pharmacological strategies and future directions in patient treatment emphasizing pleiotropic agents targeting inflammation, oxidative damage, and glutamate excitotoxicity.
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Cite this article as:
Jennings S. J., Gerber M. A. and Vallano L. M., Pharmacological Strategies for Neuroprotection in Traumatic Brain Injury, Mini-Reviews in Medicinal Chemistry 2008; 8 (7) . https://dx.doi.org/10.2174/138955708784567377
DOI https://dx.doi.org/10.2174/138955708784567377 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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