Abstract
Vitamin D deficiency is a well-established risk factor for bone disease. Emerging data suggest a pleiotropic role of this agent in a variety of functions in humans. Epidemiological studies indicate an inverse association between vitamin D deficiency and the prevalence of cardiovascular disease (CVD), as well as individual cardiometabolic risk factors, such as hypertension, diabetes, dyslipidemia and the metabolic syndrome. Moreover, vitamin D deficiency has been implicated in the atherosclerotic process.
This review considers current data regarding the role of vitamin D deficiency in the development of CVD and addresses the effect of supplementation on cardiovascular outcomes.
Keywords: Vitamin D, cardiovascular disease, hypertension, diabetes mellitus, metabolic syndrome
Current Vascular Pharmacology
Title: Vitamin D and Cardiovascular Disease: A Novel Agent for Reducing Cardiovascular Risk?
Volume: 8 Issue: 5
Author(s): Panagiotis Anagnostis, Vasilios G. Athyros, Fotini Adamidou, Matilda Florentin and Asterios Karagiannis
Affiliation:
Keywords: Vitamin D, cardiovascular disease, hypertension, diabetes mellitus, metabolic syndrome
Abstract: Vitamin D deficiency is a well-established risk factor for bone disease. Emerging data suggest a pleiotropic role of this agent in a variety of functions in humans. Epidemiological studies indicate an inverse association between vitamin D deficiency and the prevalence of cardiovascular disease (CVD), as well as individual cardiometabolic risk factors, such as hypertension, diabetes, dyslipidemia and the metabolic syndrome. Moreover, vitamin D deficiency has been implicated in the atherosclerotic process.
This review considers current data regarding the role of vitamin D deficiency in the development of CVD and addresses the effect of supplementation on cardiovascular outcomes.
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Cite this article as:
Anagnostis Panagiotis, G. Athyros Vasilios, Adamidou Fotini, Florentin Matilda and Karagiannis Asterios, Vitamin D and Cardiovascular Disease: A Novel Agent for Reducing Cardiovascular Risk?, Current Vascular Pharmacology 2010; 8 (5) . https://dx.doi.org/10.2174/157016110792006978
DOI https://dx.doi.org/10.2174/157016110792006978 |
Print ISSN 1570-1611 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6212 |
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