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Current Medicinal Chemistry

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ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

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Review Article

Tanshinone IIA: Pharmacology, Total Synthesis, and Progress in Structure-modifications

Author(s): Xing Huang, Hao Deng, Qing-kun Shen* and Zhe-Shan Quan*

Volume 29, Issue 11, 2022

Published on: 14 January, 2022

Page: [1959 - 1989] Pages: 31

DOI: 10.2174/0929867328666211108110025

Price: $65

Abstract

Tanshinone IIA, a major bioactive constituent of Danshen, a Chinese herbal medicine, has gained extensive exploration owing to its unique structural features and multiple promising biological activities. This review focuses on the pharmacology, total synthesis, and structural modifications of tanshinone IIA. We hope this review will contribute to a better understanding of the progress in the field and provide constructive suggestions for further study of tanshinone IIA.

Keywords: Tanshinone IIA, pharmacology, synthesis, structure-modifications, Salvia miltiorrhiza, Chinese medicine.

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