Abstract
This review is devoted to organic selenocyanates.
In the first part, the preparation of these compounds is reported. Organic selenocyanates have been synthesized by reaction of substrates with potassium selenocyanate, selenium diselenocyanate, diselenocyanate or selenium dicyanate. The reactions of selenenyl halides with cyanide ions or selenolates with cyanogen bromide are also efficient. In the second part, the physicochemical properties of organic selenocyanates are described. Infrared, NMR, Photoelectron and Microwave spectra are successively commented for the simplest alkyl, aryl and functionalized derivatives, viz. methyl-, phenyl-, vinyl-, ethynyl-, allyl-, propargyl-, allenyl and cyclopropylselenocyanates. The chemical reactions involving organic selenocyanates are then reported showing the diversity of applications of these compounds in the preparation of other selenium derivatives. In the last part, the recent applications of some derivatives for their antistress, antiradiation, antioxidative, antimutagenic, anticarcinogen and chemopreventive properties are summarized.
Keywords: Organic selenocyanate, preparation, physical properties, chemical reactivity, cancer therapy, chalcogens, heteroatoms, selenocyanates, tellurocyanates, acetonitrile, sigmatropic, diseleno mercury derivatives, Grignard reagent, Photoelectron Spectroscopy, NMR Spectroscopy, Microwave Spectroscopy
Current Organic Chemistry
Title: Organic Selenocyanates: Synthesis, Characterization and Uses in Chemistry and Biology
Volume: 15 Issue: 11
Author(s): Jean-Claude Guillemin
Affiliation:
Keywords: Organic selenocyanate, preparation, physical properties, chemical reactivity, cancer therapy, chalcogens, heteroatoms, selenocyanates, tellurocyanates, acetonitrile, sigmatropic, diseleno mercury derivatives, Grignard reagent, Photoelectron Spectroscopy, NMR Spectroscopy, Microwave Spectroscopy
Abstract: This review is devoted to organic selenocyanates.
In the first part, the preparation of these compounds is reported. Organic selenocyanates have been synthesized by reaction of substrates with potassium selenocyanate, selenium diselenocyanate, diselenocyanate or selenium dicyanate. The reactions of selenenyl halides with cyanide ions or selenolates with cyanogen bromide are also efficient. In the second part, the physicochemical properties of organic selenocyanates are described. Infrared, NMR, Photoelectron and Microwave spectra are successively commented for the simplest alkyl, aryl and functionalized derivatives, viz. methyl-, phenyl-, vinyl-, ethynyl-, allyl-, propargyl-, allenyl and cyclopropylselenocyanates. The chemical reactions involving organic selenocyanates are then reported showing the diversity of applications of these compounds in the preparation of other selenium derivatives. In the last part, the recent applications of some derivatives for their antistress, antiradiation, antioxidative, antimutagenic, anticarcinogen and chemopreventive properties are summarized.
Export Options
About this article
Cite this article as:
Guillemin Jean-Claude, Organic Selenocyanates: Synthesis, Characterization and Uses in Chemistry and Biology, Current Organic Chemistry 2011; 15 (11) . https://dx.doi.org/10.2174/138527211795656642
DOI https://dx.doi.org/10.2174/138527211795656642 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Advances of Heterocyclic Chemistry with Pesticide Activity
Global food safety and security will continue to be a global concern for the next 50 years and beyond. Plant diseases have had a significant impact on food safety and security throughout the entire food chain, from primary production to consumption. While conventional chemical pesticides have been traditionally used for ...read more
Calculation design of covalent/metal organic framework based catalysts
This research area combines theoretical computation and screening with machine learning for the design of covalent/metal organic framework-based catalysts, bridging the disciplines of organic chemistry, physical chemistry, computational chemistry, materials science, and machine learning. It covers several critical aspects: designing and synthesizing organic catalysts for improved performance, applying computational methods ...read more
Carbohydrates conversion in biofuels and bioproducts
Biomass pretreatment, hydrolysis, and saccharification of carbohydrates, and sugars bioconversion in biofuels and bioproducts within a biorefinery framework. Carbohydrates derived from woody biomass, agricultural wastes, algae, sewage sludge, or any other lignocellulosic feedstock are included in this issue. Simulation, techno-economic analysis, and life cycle analysis of a biorefinery process are ...read more
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Methodological Aspects and Applications of In Vivo Imaging of Apoptosis in Oncology: An Illustrative Review
Current Medical Imaging Design, Synthesis and Antibacterial Evaluation of Compounds Based on New Benzoxepine-oxime-1,2,3-triazole Hybrid
Mini-Reviews in Medicinal Chemistry Immunokinases, a Novel Class of Immunotherapeutics for Targeted Cancer Therapy
Current Pharmaceutical Design The Measurement and Mathematical Analysis of 5-Fu Release from Magnetic Polymeric Nanocapsules, following the Application of Ultrasound
Anti-Cancer Agents in Medicinal Chemistry The Real Impact of Target Therapy in Breast Cancer Patients: Between Hope and Reality
Current Cancer Drug Targets EDITORIAL [Hot Topic: Peptide-Receptor Ligands in Imaging and Therapy of Cancer (Guest Editor: Dr. Paolo Ruzza)]
Anti-Cancer Agents in Medicinal Chemistry Effects of As2O3 and Resveratrol on the Proliferation and Apoptosis of Colon Cancer Cells and the hERG-mediated Potential Mechanisms
Current Pharmaceutical Design From the Table to the Bedside: Can Food-Derived Sulforaphane be used as a Novel Agent to Treat Leukemia?
Current Cancer Drug Targets Protein-inorganic Nanohybrids: A Potential Symbiosis in Tissue Engineering
Current Drug Targets The mTOR Pathway: A New Target in Cancer Therapy
Current Cancer Drug Targets Synthesis of Novel Amides Based on Acridone Scaffold with Interesting Antineoplastic Activity
Anti-Cancer Agents in Medicinal Chemistry ZNF424 Induces Apoptosis and Inhibits Proliferation in Lung Carcinoma Cells
Current Molecular Medicine Surface Modification of Nanocarriers for Cancer Therapy
Current Nanoscience Editorial
Current Metabolomics Osteoblast Differentiation and Control by Vitamin D and Vitamin D Metabolites
Current Pharmaceutical Design Anti-Vascular Endothelial Growth Factor (VEGF) Therapy: A New Cause of Hypertension
Current Hypertension Reviews Aurora Kinase Inhibitors in Head and Neck Cancer
Current Topics in Medicinal Chemistry Contemporary Animal Models For Human Gene Therapy Applications
Current Gene Therapy The Antagonists of Endothelin Receptors: Results and Perspectives
Current Pharmaceutical Analysis Pro- and Anti-Inflammatory Cytokine Expression Levels in Macrophages; An Approach to Develop Indazolpyridin-methanones as Novel Inflammation Medication
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry