Abstract
Cancer is the second leading cause of death worldwide. Although great advancements have been made in the treatment and control of cancer progression, significant deficiencies and room for improvement remain. A number of undesired side effects sometimes occur during chemotherapy. Natural therapies, such as the use of plant-derived products in cancer treatment, may reduce adverse side effects. Currently, a few plant products are being used to treat cancer. However, a myriad of many plant products exist that have shown very promising anti-cancer properties in vitro, but have yet to be evaluated in humans. Further study is required to determine the efficacy of these plant products in treating cancers in humans. This review will focus on the various plant-derived chemical compounds that have, in recent years, shown promise as anticancer agents and will outline their potential mechanism of action.
Keywords: Medicinal plants, natural products, ayurveda, cancer, alternative medicine
Current Drug Metabolism
Title: Medicinal Plants and Cancer Chemoprevention
Volume: 9 Issue: 7
Author(s): Avni G. Desai, Ghulam N. Qazi, Ramesh K. Ganju, Mahmoud El-Tamer, Jaswant Singh, Ajit K. Saxena, Yashbir S. Bedi, Subhash C. Taneja and Hari K. Bhat
Affiliation:
Keywords: Medicinal plants, natural products, ayurveda, cancer, alternative medicine
Abstract: Cancer is the second leading cause of death worldwide. Although great advancements have been made in the treatment and control of cancer progression, significant deficiencies and room for improvement remain. A number of undesired side effects sometimes occur during chemotherapy. Natural therapies, such as the use of plant-derived products in cancer treatment, may reduce adverse side effects. Currently, a few plant products are being used to treat cancer. However, a myriad of many plant products exist that have shown very promising anti-cancer properties in vitro, but have yet to be evaluated in humans. Further study is required to determine the efficacy of these plant products in treating cancers in humans. This review will focus on the various plant-derived chemical compounds that have, in recent years, shown promise as anticancer agents and will outline their potential mechanism of action.
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Cite this article as:
Desai G. Avni, Qazi N. Ghulam, Ganju K. Ramesh, El-Tamer Mahmoud, Singh Jaswant, Saxena K. Ajit, Bedi S. Yashbir, Taneja C. Subhash and Bhat K. Hari, Medicinal Plants and Cancer Chemoprevention, Current Drug Metabolism 2008; 9 (7) . https://dx.doi.org/10.2174/138920008785821657
DOI https://dx.doi.org/10.2174/138920008785821657 |
Print ISSN 1389-2002 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5453 |
Call for Papers in Thematic Issues
Interaction between drugs and endocrine diseases
The introduction of highly active antiretroviral therapy accelerated studies and our understanding on the interaction between pharmacological therapies and endocrine diseases. Drugs can precipitate endocrine via different mechanisms, including direct alteration of hormone production and secretion, dysregulation of hormonal axis, effects on hormonal transport, receptor-binding, and cellular signalling. Common drug-induced ...read more
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