Abstract
Allergic diseases have substantially increased in all western countries and the cause of this increase would appear to be related to both environmental changes and the western lifestyle. There is a complex interaction between genetic and environmental factors that can influence the onset of allergic diseases. The activation of the innate immune system, caused by microbial stimulation, seems to have a key role in normal immune maturation. Several studies showed that the activities of intestinal microflora have a metabolic, trophic, and protective function also affecting immune tolerance. Particularly, the probiotics, live microbial food ingredients, are able to confer health benefits on the consumers. The aim of this review is summarized what is known in regard to the critical role of the probiotic on onset of allergic diseases.
Keywords: Allergic disease, allergy, children, immune tolerance, microflora, probiotics.
Current Respiratory Medicine Reviews
Title:Probiotics Role in Allergic Illness
Volume: 13 Issue: 1
Author(s): Michele Miraglia del Giudice*, Cristiana Indolfi, Giuseppe Fabio Parisi, Amalia Coronella, Annalisa Allegorico and Nunzia Maiello
Affiliation:
- Department of Women, Child and General and Specialist Surgery, University of Campania “Luigi Vanvitelli” Napoli,Italy
Keywords: Allergic disease, allergy, children, immune tolerance, microflora, probiotics.
Abstract: Allergic diseases have substantially increased in all western countries and the cause of this increase would appear to be related to both environmental changes and the western lifestyle. There is a complex interaction between genetic and environmental factors that can influence the onset of allergic diseases. The activation of the innate immune system, caused by microbial stimulation, seems to have a key role in normal immune maturation. Several studies showed that the activities of intestinal microflora have a metabolic, trophic, and protective function also affecting immune tolerance. Particularly, the probiotics, live microbial food ingredients, are able to confer health benefits on the consumers. The aim of this review is summarized what is known in regard to the critical role of the probiotic on onset of allergic diseases.
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Cite this article as:
del Giudice Miraglia Michele *, Indolfi Cristiana , Parisi Fabio Giuseppe , Coronella Amalia , Allegorico Annalisa and Maiello Nunzia , Probiotics Role in Allergic Illness, Current Respiratory Medicine Reviews 2017; 13 (1) . https://dx.doi.org/10.2174/1573398X13666170821113226
DOI https://dx.doi.org/10.2174/1573398X13666170821113226 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
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