Relationship Between Calcium Intake and Impaired Activities of Daily Living in a Japanese Population: NIPPON DATA90

Mana Kogure; Naho Tsuchiya; Akira Narita; Takumi Hirata; Naoki Nakaya; Tomohiro Nakamura; Atsushi Hozawa; Takehito Hayakawa; Nagako Okuda; Naoko Miyagawa; Aya Kadota; Takayoshi Ohkubo; Yoshitaka Murakami; Kiyomi Sakata; Katsuyuki Miura; Akira Okayama; Tomonori Okamura; Hirotsugu Ueshima

doi:10.2188/jea.JE20190234

Original Article

Relationship Between Calcium Intake and Impaired Activities of Daily Living in a Japanese Population: NIPPON DATA90

Mana Kogure, Naho Tsuchiya, Akira Narita, Takumi Hirata, Naoki Nakaya, Tomohiro Nakamura, Atsushi Hozawa, Takehito Hayakawa, Nagako Okuda, Naoko Miyagawa, Aya Kadota, Takayoshi Ohkubo, Yoshitaka Murakami, Kiyomi Sakata, Katsuyuki Miura, Akira Okayama, Tomonori Okamura, Hirotsugu Ueshima

Author information

Mana Kogure
https://orcid.org/0000-0003-2585-2405
Division of Personalized Prevention and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University
Naho Tsuchiya
Division of Personalized Prevention and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University
Akira Narita
Division of Personalized Prevention and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University
Takumi Hirata
Division of Personalized Prevention and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University
Department of Public Health, Hokkaido University Faculty of Medicine
Naoki Nakaya
Division of Personalized Prevention and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University
Department of Health Sciences, Saitama Prefectural University
Tomohiro Nakamura
Division of Personalized Prevention and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University
Atsushi Hozawa
https://orcid.org/0000-0002-8031-8523
Division of Personalized Prevention and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University
Takehito Hayakawa
Research Center for Social Studies of Health and Community, Ritsumeikan University
Nagako Okuda
https://orcid.org/0000-0002-6893-0509
Department of Health and Nutrition, University of Human Arts and Sciences
Naoko Miyagawa
International Center for Nutrition and Information, National Institute of Health and Nutrition
Aya Kadota
https://orcid.org/0000-0001-7378-0544
Department of Public Health, Shiga University of Medical Science
Center for Epidemiologic Research in Asia, Shiga University of Medical Science
Takayoshi Ohkubo
https://orcid.org/0000-0002-3283-8196
Department of Hygiene and Public Health, Teikyo University School of Medicine
Yoshitaka Murakami
Department of Medical Statistics, Faculty of Medicine, Toho University
Kiyomi Sakata
Department of Hygiene and Public Health, Iwate Medical University
Katsuyuki Miura
https://orcid.org/0000-0002-2646-9582
Department of Public Health, Shiga University of Medical Science
Center for Epidemiologic Research in Asia, Shiga University of Medical Science
Akira Okayama
https://orcid.org/0000-0002-5086-6385
Research Institute of Strategy for Prevention
Tomonori Okamura
https://orcid.org/0000-0003-0488-0351
Department of Preventive Medicine and Public Health, Keio University School of Medicine
Hirotsugu Ueshima
https://orcid.org/0000-0002-7742-4253
Department of Public Health, Shiga University of Medical Science
Center for Epidemiologic Research in Asia, Shiga University of Medical Science

Keywords: bootstrap analyses, calcium intake, impaired activities of daily living, nested case-control study, NIPPON DATA90

JOURNAL OPEN ACCESS

2021 Volume 31 Issue 2 Pages 119-124

DOI https://doi.org/10.2188/jea.JE20190234

Browse “Advance online publication” version

Details

Abstract

Background: Major reasons for long-term care insurance certification in Japan are stroke, dementia, and fracture. These diseases are reported to be associated with calcium intake. This study examined the association between calcium intake and impaired activities of daily living (ADL) using the data from NIPPON DATA90, consisting of representative sample of the Japanese population.

Methods: A population-based nested case-control study was performed. A baseline survey was conducted in 1990, followed by ADL surveys of individuals ≥65 years old in 2000. Individuals with impaired ADL and selected age- and sex-matched controls were then identified. We obtained 132 pairs. Calcium intake was energy-adjusted using the residual method. The association between calcium intake and impaired ADL was examined using conditional logistic regression models. To assess the accuracy of the estimates, we conducted bootstrap analyses.

Results: The adjusted odds ratios (ORs) for impaired ADL compared with the group with a calcium intake of <476 mg/day were 0.72 (95% confidence interval [CI], 0.37–1.40) for the 476–606 mg/day group and 0.44 (95% CI, 0.21–0.94) for the ≥607 mg/day group in 2000 (P for linear trend = 0.03). After the bootstrap analyses, the inverse relationship unchanged (median OR per 100-mg rise in calcium intake, 0.87 [1,000 resamplings]; 95% CI, 0.76–0.97).

Conclusions: After bootstrap analyses, calcium intake was inversely associated with impaired ADL 10 years after the baseline survey.

Corresponding author

Funder information

1.Fund name: Ministry of Health, Labour and Welfare

Register with J-STAGE for free!