doiSerbia

Investigation on antibacterial synergism of Origanum vulgare and Thymus vulgaris essential oils

Stojković D. (Institute for Biological Research “Siniša Stanković”, Department of Plant Physiology, Belgrade)
Glamočlija Jasmina (Institute for Biological Research “Siniša Stanković”, Department of Plant Physiology, Belgrade)
Ćirić Ana (Institute for Biological Research “Siniša Stanković”, Department of Plant Physiology, Belgrade)
Nikolić M. (Institute for Biological Research “Siniša Stanković”, Department of Plant Physiology, Belgrade)
Ristić M. (Institute for Medicinal Plant Research “Josif Pančić”, Belgrade)
Šiljegović Jovana (Institute for Biological Research “Siniša Stanković”, Department of Plant Physiology, Belgrade)
Soković Marina (Institute for Biological Research “Siniša Stanković”, Department of Plant Physiology, Belgrade)

Essential oils are well known as strong antimicrobial agents of plant origin. In spite of this, the antimicrobial synergism of essential oils isolated from different plant species is poorly investigated. The following study examines the synergism of the essential oils of Origanum vulgare L. and Thymus vulgaris L against pathogenic bacteria, Staphylococcus aureus and Salmonella typhimurium. First, the antibacterial effect of the oils was tested, and the minimal inhibitory concentrations (MIC) of both oils were determined using the microdilution method. To test whether the oils act synergistically, every possible combination of essential oil concentrations was used in a dynamic checkerboard method. The results indicated that the oils indeed acted synergistically with fractional inhibitory concentration indexes of 0.45 and 0.50. [Projekat Ministarstva nauke Republike Srbije, br. 173032]

This article has been corrected. Link to the correction 10.2298/ABS150713085E