Journal of the Serbian Chemical Society 2012 Volume 77, Issue 4, Pages: 407-413
https://doi.org/10.2298/JSC110427189T
Full text (
646 KB)
Cited by
Synthesis of biscoumarin derivatives by the reaction of aldehydes and 4-hydroxycoumarin using ruthenium (III) chloride hydrate as a versatile homogeneous catalyst
Tabatabaeian Khalil (Department of Chemistry, Faculty of Sciences, University of Guilan, Iran)
Heidari Hannaneh (Department of Chemistry, Faculty of Sciences, University of Guilan, Iran)
Khorshidi Alireza (Department of Chemistry, Faculty of Sciences, University of Guilan, Iran)
Mamaghani Manouchehr (Department of Chemistry, Faculty of Sciences, University of Guilan, Iran)
Mahmoodi Nosrat O. (Department of Chemistry, Faculty of Sciences, University of Guilan, Iran)
The one-pot domino Knoevenagel-type condensation/Michael reaction of
aromatic, heteroaromatic and aliphatic aldehydes with 4-hydroxycoumarin in
aqueous media in the presence of ruthenium salt as homogeneous catalyst was
investigated. It was found that 5 mol% of RuCl3.nH2O catalyzes biscoumarin
synthesis in high yields (70-95%) under optimised, mild, green and
environmentally benign reaction conditions in short times (25-35min).
Keywords: ruthenium, biscoumarin, aldehyde, 4-hydroxycoumarin, homogeneous catalyst, condensation reaction