doiSerbia

Cerium doped hydroxyapatite nanoparticles synthesized by coprecipitation method

Ciobanu Carmen Steluta (National Institute of Materials Physics, Magurele, Romania + University Politehnica of Bucharest, Faculty of Applied Chemistry and Materials Science, Department of Science and Engineering of Oxide Materials and Nanomaterials, Bucharest, Romania)
Popa Cristina Liana (National Institute of Materials Physics, Magurele, Romania)
Predoi Daniela (National Institute of Materials Physics, Magurele, Romania)

The present work reports a simple coprecipitation adapted method for the synthesis of stable Ce substituted to Ca hydroxyapatite (HAp) nanoparticles. The structural and morphological properties of Ce doped hydroxyapatite (Ce:HAp) were characterized by X-ray diffraction (XRD), Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray analysis (EDAX). The optical properties of Ce doped hydroxyapatite were also investigated using Fourier Transform Infrared (FTIR) spectroscopy, FT Raman spectroscopy and photoluminescence analysis. The results of the XRD studies revealed the progressive increase in the a- and c-axes with increasing of Ce concentrations. In the FTIR studies of Ce:HAp powders a similar structure to hydroxyapatite was observed. IR and Raman wavenumbers and the peak strength of the bands associated to the P-O and O-H bonds decreases progressively with the increase of Ce concentration. All the emission maxima could be attributed to the 5d-4f transitions of Ce ions. The displacement of maximum emission bands with the increase of Cerium in the samples is in agreement with the results obtained by XRD studies. The Ce:HAp samples with xCe =0.03 and 0.05 exhibited significant antibacterial activity against Staphylococcus aureus ATCC 6538 and E. coli 714 bacterial strains compared to Ce:HAp samples with xCe =0 (pure HAp) and 0.01.

Keywords: biomaterials, FTIR, FT Raman, photoluminescence, Staphylococcus aureus ATCC 6538, Escherichia. coli 714