The purpose of this study was to investigate the clinical effect of K dentifrice containing three types of active agents on the improvement of periodontal disease. These agents are sodium chloride, ε-amino caproic acid and aluminium chlorohydroxy allantoinate. Also the effect of toothbrushes having different hardness of bristle was examined.
Forty-three outpatients were divided into 4 groups: Group 1, K dentifrice and S brush; Group 2, B dentifrice (placebo) and S brush; Group 3, K dentifrice and M brush; and Group 4, B dentifrice and M brush. The tooth-brushing was performed by all subjects with the Rolling method three times a day for two weeks.
The clinical effect was observed using analysis of variance for P-M-A index reduction ratio of the score at the initial examination to the score one and two weeks after.
The results showed a statistically significant (P<0.01) difference between K and B dentifrices. The K dentifrice was superior to the B dentifrice. After two weeks the mean P-M-A index reduction ratio of the K dentifrice and B dentifrice were 47.6% and 36.8%, respectively.
There was no difference between toothbrushes S and M. These results showed that K dentifrice containing sodium chloride, ε-amino caproic acid and aluminium chlorohydroxy allantoinate was effective for the improvement of periodontal disease.