Host Defence Against Candida albicans and the Role of Pattern-recognition Receptors
DOI:
https://doi.org/10.2340/00015555-1250Keywords:
Candida albicans, pattern-recognition receptor, pathogen-associated molecular pattern, C-type lectin receptor, toll-like receptor.Abstract
Recognition of Candida albicans is mediated by several classes of pattern-recognition receptors, including Toll-like receptors and C-type lectin receptors. Cell wall components of C. albicans, interact with the pattern-recognition receptors, which are expressed by different cells, primarily antigen-presenting cells. This review aims to discuss the different pattern-recognition receptors responsible for recognition of special structures of C. albicans, which are known to activate intracellular signals that finally lead to directed and efficient host defence.Downloads
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Copyright (c) 2011 Gerd G. Gauglitz, Helene Callenberg, Günther Weindl, Hans C. Korting
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