Methotrexate Use and Monitoring in Patients with Psoriasis: A Consensus Report Based on a Danish Expert Meeting

Authors

  • Line Raaby
  • Claus Zachariae
  • Monika Østensen
  • Lene Heickendorff
  • Peter Thielsen
  • Henning Grønbæk
  • Lone Skov
  • Nini Kyvsgaard
  • Jakob T. Madsen
  • Michael Heidenheim
  • Anne T. Funding
  • Gitte Strauss
  • Rune Lindberg
  • Lars Iversen

DOI:

https://doi.org/10.2340/00015555-2599

Abstract

Methotrexate (MTX) has been used in the treatment of psoriasis and other dermatological diseases for more than 50 years. However, there is limited evidence regarding its effect, dose and monitoring, and a lack of consensus regarding how the drug should be used in daily practice. Although the use of MTX is governed by guidelines, such as the European S3-Guidelines and the National Institute for Health and Care Excellence (NICE) guideline, it is important to discuss and adjust these guidelines to national standards. An expert meeting was held in Denmark at the end of 2014, in order to reach consensus regarding the use of MTX in dermatological practice in Denmark. Participants included dermatologists, hepatologists, paediatricians, clinical biochemists and a rheumatologist. Topics discussed were: liver disease monitoring, teratogenic effects of MTX, risk of cancer, and use of MTX in children. We report here the conclusions of this expert meeting regarding use of MTX in dermatological practice.

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Published

2017-01-09

How to Cite

Raaby, L., Zachariae, C., Østensen, M., Heickendorff, L., Thielsen, P., Grønbæk, H., Skov, L., Kyvsgaard, N., Madsen, J. T., Heidenheim, M., Funding, A. T., Strauss, G., Lindberg, R., & Iversen, L. (2017). Methotrexate Use and Monitoring in Patients with Psoriasis: A Consensus Report Based on a Danish Expert Meeting. Acta Dermato-Venereologica, 97(4), 426–432. https://doi.org/10.2340/00015555-2599

Issue

Vol. 97 No. 4 (2017)

Section

Articles

License

Copyright (c) 2017 Line Raaby, Claus Zachariae, Monika Østensen, Lene Heickendorff, Peter Thielsen, Henning Grønbæk, Lone Skov, Nini Kyvsgaard, Jakob T. Madsen, Michael Heidenheim, Anne T. Funding, Gitte Strauss, Rune Lindberg, Lars Iversen

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.

Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.

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