ORIGINAL ARTICLE  EPIDEMIOLOGY AND CLINICAL MEDICINE 

The Journal of Sports Medicine and Physical Fitness 2018 March;58(3):295-308

DOI: 10.23736/S0022-4707.16.06565-8

Copyright © 2016 EDIZIONI MINERVA MEDICA

language: English

The effect of exercise induced weight-loss on myokines and adipokines in overweight sedentary females: steps-aerobics vs. jogging-walking exercises

Halil DUZOVA ¹ ✉, Esin GULLU ², Guner CICEK ³, Burcu K. KOKSAL ¹, Basak KAYHAN ⁴, Abdullah GULLU ², Ibrahim SAHIN ⁵

¹ Department of Physiology, Medical School, Inonu University, Malatya, Turkey; ² Physical Education and Sports High School, Inonu University, Malatya, Turkey; ³ Physical Education and Sports High School, Hitit University, Corum, Turkey; ⁴ Department of Medical Biology and Genetics, Inonu University, Medical School, Malatya, Turkey; ⁵ Department of Endocrinology, Inonu University, Medical School, Malatya, Turkey

BACKGROUND: The objectives of this study were to verify effects of step-aerobic exercise (SAE) and jogging-walking exercise (JWE) program on myokines and adipokines levels in overweight sedentary females.
METHODS: Volunteer subjects (N.=25) were assigned to two exercise groups: steps aerobics and jogging-walking. The exercise program given to them was for five days a week and for twelve weeks period. Serum samples were collected from venous blood before and immediately after Cardio-Respiratory Fitness Test (CRF) by Bruce protocol and stored at -80 °C until they were assayed before 12 weeks exercise program. After 12-weeks training program this procedure was repeated. Serum TNF-α, IL-6, IL-15, IL-17, IL-18, leptin, resistin and adiponectin levels were assayed by ELISA.
RESULTS: Leptin and IL-15 levels were increased whereas resistin levels were decreased after CRF Test in JWE training group following 12-weeks exercise program. TNF-α, IL-15 and IL-18 levels were higher and leptin levels were lower in SAE group than JWE group after 12-weeks exercise period. However, both SAE and JWE did not lead to significant change in serum levels of IL-17, IL-6 and adiponectin levels.
CONCLUSIONS: This study has added to existing knowledge that both SAE and JWE may cause weight loss especially in fat mass. But, the effect of SAE and JWE on myokines and adipokines levels may be the different. Further studies are needed to find out clinical importance of these findings.

KEY WORDS: Exercise - Jogging - Interleukin-15 - Interleukin-17 - Interleukin-18 - Resistin