Systematic review and cost effectiveness evaluation of 'pill-in-the-pocket' strategy for paroxysmal atrial fibrillation compared to episodic in-hospital treatment or continuous antiarrhythmic drug therapy

Martin Saborido, C; Hockenhull, J; Bagust, A; Boland, A; Dickson, R; Todd, D

doi:10.3310/hta14310

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Study found that a pill-in-the-pocket (PiP) strategy seems to be slightly less effective than antiarrhythmic drug therapy and in-hospital treatment but is associated with cost savings. A change in clinical practice that includes the introduction of PiP may save costs but also involves a reduction in clinical effectiveness compared to existing approaches used to treat patients with paroxysmal atrial fibrillation (PAF); however, there is insufficient evidence to support a recommendation for the use of PiP strategy in patients with PAF

C Martin Saborido, J Hockenhull, A Bagust, A Boland, R Dickson & D Todd.

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C Martin Saborido ¹, J Hockenhull ¹, A Bagust ¹, A Boland ¹, R Dickson ^1,^*, D Todd ²

¹ Liverpool Reviews and Implementation Group (LRiG), Liverpool, UK
² Liverpool Heart & Chest Hospital, Liverpool, UK
^* Corresponding author Email:

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