American pikas (Ochotona princeps) are small alpine lagomorphs and talus obligates with a narrow range of temperature tolerance, along with physiological and ecological characteristics that make them especially vulnerable to local extirpation in the face of climate change. Since their initial colonization of the Great Basin during the Pleistocene geological epoch, the distribution of pikas in this region has become more restricted, with population losses occurring especially in lower-elevation sites characterized by relatively low precipitation and high temperatures. Even where pikas have persisted, many populations are now restricted to higher elevations. We surveyed several sites in the Bodie Hills of eastern California known to have been recently occupied by pikas. Here we report the recent extirpations of 2 of these sites: one small cluster of anthropogenic patches in the historic Masonic Mining District and one natural patch on Masonic Mountain. These extirpations are consistent with those reported in California and across the Great Basin and may indicate the impending loss of pikas from this region due to impacts from global climate change.