Korean J Occup Environ Med. 2012 Sep;24(3):274-286. Korean.
Published online Sep 30, 2012.
Copyright © 2012 The Korean Society of Occupational and Environmental Medicine
Original Article

The Association between Shift Work and Bone Mineral Density : analysis of 2008–2009 Korean National Health and Nutrition Examination Survey

Jong Ho Wang, Goeun Lee, Jun-Taek Song, Jongho Kwon, Hyunrim Choi, Kyunghee Jung-Choi,1 and Sinye Lim
    • Department of Occupational and Environmental Medicine, Kyung Hee University Hospital, Korea.
    • 1Department of Preventive Medicine, Ewha Womans University School of Medicine, Korea.
Received July 20, 2012; Revised September 24, 2012; Accepted September 24, 2012.

Abstract

Objectives

The objectives of this study were to explore the association between shift work and the bone mineral density in a representative sample of Korean workers.

Methods

He data from the Fourth Korean National Health and Nutrition Examination Survey (2008-2009) was used. The participants were Korean workers aged 16 to 60 years. Logistic regression analysis was applied to determine the association between shift work and the bone mineral density after controlling for covariates using the SAS version 9.3 package program.

Results

The blood vitamin D level in shift workers was significantly lower than that of day workers in both males and females. In male shift workers, shift work was significantly associated with a decreased bone mineral density in the femoral neck (odds ratio(OR) 1.42, 95% confidence interval(CI)=1.05~1.92) and lumbar spine (OR 1.53, 95% CI=1.09~2.15) compared to day workers. After controlling for covariates, this association was still significant. In the case of female shift workers, shift work was significantly related to a decreased bone mineral density in the total femur (OR 2.84, 95% CI=1.69~4.79) and lumbar spine (OR 1.58, 95% CI=1.12~2.24). After controlling for covariates, this risk was not statistically significant.

Conclusions

The blood vitamin D level of shift workers was significantly lower than that of day workers. In male shift workers, shift work can decrease the bone mineral density in the femoral neck and lumbar spine. Prospective studies with information on the shift work intensity and duration and exposuredata to explain mechanisms will be needed.

Keywords
Shift work; Work schedule tolerance; Bone density; Vitamin D


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