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Case Report

Successful Management of a Childhood Osteosarcoma with Epiphysiolysis and Distraction Osteogenesis

1
Orthopaedic Department, General Hospital of Jinan Military Region, Jinan, China
2
Department of Orthopaedic Surgery, Tangdu Hospital, Xi’an, China
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2014, 21(4), 658-662; https://0-doi-org.brum.beds.ac.uk/10.3747/co.21.1956
Submission received: 8 May 2014 / Revised: 9 June 2014 / Accepted: 6 July 2014 / Published: 1 August 2014

Abstract

In an 11-year-old boy with osteosarcoma in the proximal tibia (type iii), 2 cycles of dia chemotherapy (cisplatin, ifosfamide, doxorubicin) were administered preoperatively while epiphysiolysis was performed. Clinical response was determined to be complete by radiography and histopathology. Marginal excision was then performed with preservation of the proximal tibial epiphysis. Metaphyseal reconstruction was performed using distraction osteogenesis. Six cycles of dia chemotherapy were administered postoperatively. Twenty months later, the patient had developed no complications and experienced full bone healing, with no limb discrepancy. In selected adolescent patients with osteosarcoma, in whom the tumour is in full contact with the epiphysis, epiphyseal preservation by epiphysiolysis and reconstruction by distraction osteogenesis can provide an excellent outcome, resulting in a stable reconstruction that functionally restores the native limb.
Keywords: osteosarcoma; epiphysis preservation; epiphysiolysis; distraction osteogenesis; limb function; quality of life osteosarcoma; epiphysis preservation; epiphysiolysis; distraction osteogenesis; limb function; quality of life

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MDPI and ACS Style

Xu, S.F.; Yu, X.C.; Xu, M.; Chen, X. Successful Management of a Childhood Osteosarcoma with Epiphysiolysis and Distraction Osteogenesis. Curr. Oncol. 2014, 21, 658-662. https://0-doi-org.brum.beds.ac.uk/10.3747/co.21.1956

AMA Style

Xu SF, Yu XC, Xu M, Chen X. Successful Management of a Childhood Osteosarcoma with Epiphysiolysis and Distraction Osteogenesis. Current Oncology. 2014; 21(4):658-662. https://0-doi-org.brum.beds.ac.uk/10.3747/co.21.1956

Chicago/Turabian Style

Xu, S.F., X.C. Yu, M. Xu, and X. Chen. 2014. "Successful Management of a Childhood Osteosarcoma with Epiphysiolysis and Distraction Osteogenesis" Current Oncology 21, no. 4: 658-662. https://0-doi-org.brum.beds.ac.uk/10.3747/co.21.1956

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