Journal of Clinical and Experimental Hematopathology
Online ISSN : 1880-9952
Print ISSN : 1346-4280
ISSN-L : 1346-4280
Review Article
Interdigitating Dendritic Cell Sarcoma and Follicular Dendritic Cell Sarcoma : Histopathological Findings for Differential Diagnosis
Hiroya OhtakeMitsunori Yamakawa
Author information
JOURNAL FREE ACCESS

2013 Volume 53 Issue 3 Pages 179-184

Details
Abstract

Both interdigitating cell sarcoma (IDCS) and follicular dendritic cell sarcoma (FDCS) are rare neoplasms derived from dendritic cells in lymphoid organs. IDCS is defined as a neoplastic proliferation of spindle-shaped to ovoid cells with phenotypic features similar to those of IDCs. FDCS is a malignant neoplasm derived from FDCs that possess and present antigens to B cells in the follicular (germinal) centers of lymphoid organs. They often occur in lymph nodes, although they can also arise at extranodal sites. In this review, we have highlighted the morphological and immunohistochemical properties of these neoplasms, which could help in unequivocal and accurate diagnosis. [J Clin Exp Hematop 53(3) : 179-184, 2013]

Content from these authors
© 2013 by The Japanese Society for Lymphoreticular Tissue Research
Next article
feedback
Top