Home Acta Virologica 2015 Acta Virologica Vol.59, No.4, p.389-397, 2015

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Quarterly,
Founded: 1957
ISSN 0001-723X
E-ISSN 1336-2305

Published in English

Impact Factor = 1.82

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Acta Virologica Vol.59, No.4, p.389-397, 2015

Title: Differentially expressed genes in healthy and plum pox virus-infected Nicotiana benthamiana plants
Author: Z. VOZÁROVÁ , M. ŽILOVÁ , Z. ŠUBR
Abstract: Viruses use both material and energy sources of their hosts and redirect the production of disposable compounds in order to make viral replication more efficient. Metabolism of infected organisms is modified by these enhanced requirements as well by their own defense response. Resulting complex story consists of many regulation events on various gene expression levels. Elucidating these processes may contribute to the knowledge on virus-host interactions and to evolving new antiviral strategies. In our work we applied a subtractive cloning technique to compare the transcriptomes of healthy and plum pox virus (PPV)-infected Nicotiana benthamiana plants. Several genes were found to be induced or repressed by the PPV infection. The induced genes were mainly related to general stress response or photosynthesis, several repressed genes could be connected with growth defects evoked by the infection. Interestingly, some genes usually up-regulated by fungal or bacterial infection were found repressed in PPV-infected plants. Potential involvement of particular differently expressed genes in the process of PPV infection is discussed.
Keywords: virus-host interaction; gene expression; subtractive hybridization
Published online: 06-Dec-2015
Year: 2015, Volume: 59, Issue: 4 Page From: 389, Page To: 397
doi:10.4149/av_2015_04_389


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