International Journal of Academic Research in Psychology

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The Relationship between Anxiety, Depression, and Quality of Life among Women with Breast Cancer

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Anxiety and depression, as common psychological disturbances among patients with breast cancer, might negatively influence their quality of life. The present study aims to explore the relationship between anxiety and depression, in one hand, and quality of life, in the other hand, among these patients. In the present correlational study, 97 women with breast cancer referring to Seyedoshohada Hospital, Isfahan, Iran, were selected through simple random sampling. The participants filled out Life Orientation Test (LOT), Snyder Adult Hope Scale, and Hospital Anxiety and Depression Scale (HADS). Pearson product moment correlation and independent samples t-test were run in SPSS (version 22) to analyze the data. The mean of anxiety, depression, and Quality of Life were 10.21±4.79, 8.31±4.74, and 63.74±19.20, respectively. The total score of anxiety and depression was 18.53±9.02. The Pearson correlation coefficient indicated a statistically significant inverse relationship between Quality of Life and anxiety (r=-.48, p<.01) as well as depression (r=-.52, p<.01), indicating patients with more anxiety and depression had lower quality of life. Therefore, it is highly suggested that, along with conventional treatments, initial assessment and screening of anxiety and depression be paid more attention, and necessary interventions be made to reduce them among patients with breast cancer, enhancing these patients’ quality of life.
Alacacioglu, A., Binicier, O., Gungor, O., Oztop, I., Dirioz, M., & Yilmaz, U. (2010). Quality of life, anxiety, and depression in Turkish colorectal cancer patients. Supportive care in cancer, 18(4), 417-421.
Bektas, D. K., & Demir, S. (2016). Anxiety, Depression Levels and Quality of Life in Patients with Gastrointestinal Cancer in Turkey. Asian Pacific Journal of Cancer Prevention, 17(2), 723-731.
Bredal, I. S., Sandvik, L., Karesen, R., & Ekeberg, O. (2011). Prognostic value of health?related quality?of?life parameters in early?stage breast cancer: an 8?year follow?up study. Psycho?Oncology, 20(10), 1102-1107.
Brown, D. J., McMillan, D. C., & Milroy, R. (2005). The correlation between fatigue, physical function, the systemic inflammatory response, and psychological distress in patients with advanced lung cancer. Cancer, 103(2), 377-382.
Buzgova, R., Jarosova, D., & Hajnova, E. (2015). Assessing anxiety and depression with respect to the quality of life in cancer inpatients receiving palliative care. European Journal of Oncology Nursing, 19(6), 667-672.
Dedeli, O., Fadiloglu, C., & Uslu, R. (2008). A survey of functional living and social support in patients with cancer. J Turk Oncol, 23, 132-139.
Demir, M. (2015). Effects of Laughter Therapy on Anxiety, Stress, Depression and Quality of Life in Cancer Patients. Journal of Cancer Science & Therapy, 2015.
Drell IV, T., Joseph, J., Lang, K., Niggemann, B., Zaenker, K., & Entschladen, F. (2003). Effects of neurotransmitters on the chemokinesis and chemotaxis of MDA-MB-468 human breast carcinoma cells. Breast cancer research and treatment, 80(1), 63-70.
Ell, K., Sanchez, K., Vourlekis, B., Lee, P.-J., Dwight-Johnson, M., Lagomasino, I., . . . Russell, C. (2005). Depression, correlates of depression, and receipt of depression care among low-income women with breast or gynecologic cancer. Journal of Clinical Oncology, 23(13), 3052-3060.
Ferrell, B. R., Grant, M., Funk, B., Otis-Green, S., & Garcia, N. (1997). Quality of life in breast cancer: Part I: Physical and social well-being. Cancer Nursing, 20(6), 398-408.
Frick, E., Tyroller, M., & Panzer, M. (2007). Anxiety, depression and quality of life of cancer patients undergoing radiation therapy: a cross?sectional study in a community hospital outpatient centre. European journal of cancer care, 16(2), 130-136.
Hussein, I. (2011). The relationship between perfectionism and loneliness, and quality of life of medical students in Guilan province. M.S. Thesis, Islamic Azad University of Tonokabon.
Hutter, N., Vogel, B., Alexander, T., Baumeister, H., Helmes, A., & Bengel, J. (2013). Are depression and anxiety determinants or indicators of quality of life in breast cancer patients? Psychology, health & medicine, 18(4), 412-419.
Karakas, S. A., & Okanli, A. (2014). The relationship between meaning of illness, anxiety depression, and quality of life for cancer patients. Collegium antropologicum, 38(3), 939-944.
Karakoyun-Celik, O., Gorken, I., Sahin, S., Orcin, E., Alanyali, H., & Kinay, M. (2010). Depression and anxiety levels in woman under follow-up for breast cancer: relationship to coping with cancer and quality of life. Medical Oncology, 27(1), 108-113.
Kavrad?m, S. T., & Ozer, Z. C. (2014). Hope in patients with cancer. Psikiyatride Guncel Yaklasimlar-Current Approaches in Psychiatry, 6(2), 154-164.
Kutlu, R., Civi, S., Borüban, M., & Demir, A. (2011). Depression and the factors affecting the quality of life in cancer patients. SelCuk Üniv T?p Derg, 27(3), 149-153.
Li, Y., & Yuan, C. (2011). Levels of fatigue in Chinese women with breast cancer and its correlates: A cross?sectional questionnaire survey. Journal of the American Academy of Nurse Practitioners, 23(3), 153-160.
Massie, M. J., & Holland, J. C. (1987). The cancer patient with pain: psychiatric complications and their management. The Medical clinics of North America, 71(2), 243.
Misono, S., Weiss, N. S., Fann, J. R., Redman, M., & Yueh, B. (2008). Incidence of suicide in persons with cancer. Journal of Clinical Oncology, 26(29), 4731-4738.
Ng, C., Mohamed, S., See, M., Harun, F., Sulaiman, A., Zainal, N., & Taib, N. (2016). Anxiety, depression, perceived social support and quality of life in Malaysian breast cancer patients: A 1-year prospective study. European Psychiatry, 33, S419.
Nikbakhsh, N., Moudi, S., Abbasian, S., & Khafri, S. (2014). Prevalence of depression and anxiety among cancer patients. Caspian J Intern Med, 5(3), 167-170.
O’Neil, A., Stevenson, C. E., Williams, E. D., Mortimer, D., Oldenburg, B., & Sanderson, K. (2013). The health-related quality of life burden of co-morbid cardiovascular disease and major depressive disorder in Australia: findings from a population-based, cross-sectional study. Quality of life research, 22(1), 37-44.
Ozkan, S., Ogce, F., & Koca, A. (2007). Determination of the presence of depression, anxiety and disability of breast and gastro intestinal system cancer patients. J Ege University School of Nursing, 23, 69-80.
Pandey, M., Sarita, G. P., Devi, N., Thomas, B. C., Hussain, B. M., & Krishnan, R. (2006). Distress, anxiety, and depression in cancer patients undergoing chemotherapy. World Journal of Surgical Oncology, 4(1), 1.
Petrie, W., Logan, J., & DeGrasse, C. (2001). Research review of the supportive care needs of spouses of women with breast cancer. Paper presented at the Oncology nursing forum.
Rajandram, R. K., Ho, S. M., Samman, N., Chan, N., McGrath, C., & Zwahlen, R. A. (2011). Interaction of hope and optimism with anxiety and depression in a specific group of cancer survivors: a preliminary study. BMC research notes, 4(1), 519.
Safaee, A., & Dehkordi, M. B. (2007). Validation study of a quality of life (QOL) questionnaire for use in Iran. Asian Pac J Cancer Prev, 8(4), 543-546.
Satin, J. R., Linden, W., & Phillips, M. J. (2009). Depression as a predictor of disease progression and mortality in cancer patients. Cancer, 115(22), 5349-5361.
Schleife, H., Sachtleben, C., Barboza, C. F., Singer, S., & Hinz, A. (2014). Anxiety, depression, and quality of life in German ambulatory breast cancer patients. Breast Cancer, 21(2), 208-213.
Schmid?Büchi, S., Halfens, R. J., Dassen, T., & Van Den Borne, B. (2008). A review of psychosocial needs of breast?cancer patients and their relatives. Journal of clinical nursing, 17(21), 2895-2909.
Shim, E.-J., Mehnert, A., Koyama, A., Cho, S.-J., Inui, H., Paik, N.-S., & Koch, U. (2006). Health-related quality of life in breast cancer: A cross-cultural survey of German, Japanese, and South Korean patients. Breast cancer research and treatment, 99(3), 341-350.
Singer, S., Das-Munshi, J., & Brähler, E. (2009). Prevalence of mental health conditions in cancer patients in acute care—a meta-analysis. Annals of Oncology, mdp515.
Skarstein, J., Aass, N., Fosså, S. D., Skovlund, E., & Dahl, A. A. (2000). Anxiety and depression in cancer patients: relation between the Hospital Anxiety and Depression Scale and the European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire. Journal of psychosomatic research, 49(1), 27-34.
So, W. K., Marsh, G., Ling, W., Leung, F., Lo, J. C., Yeung, M., & Li, G. K. (2010). Anxiety, depression and quality of life among Chinese breast cancer patients during adjuvant therapy. European Journal of Oncology Nursing, 14(1), 17-22.
Spencer, S., Carver, C. S., & Price, A. (1998). Psychological and social factors in adaptation. Psycho-oncology, 2, 211-222.
Srivastava, V., Ansari, M. A., Kumar, A., Shah, A. G., Meena, R. K., Sevach, P., & Singh, O. P. (2016). Study of Anxiety and Depression among Breast Cancer Patients from North India. Clinical Psychiatry.
Su, F., Ouyang, N., Zhu, P., Ouyang, N., Jia, W., Gong, C., . . . Song, E. (2005). Psychological stress induces chemoresistance in breast cancer by upregulating mdr1. Biochemical and biophysical research communications, 329(3), 888-897.
Tavoli, A., Mohagheghi, M. A., Montazeri, A., Roshan, R., Tavoli, Z., & Omidvari, S. (2007). Anxiety and depression in patients with gastrointestinal cancer: does knowledge of cancer diagnosis matter? BMC gastroenterology, 7(1), 1.
Tel, H., Tel, H., & Do?an, S. (2011). Fatigue, anxiety and depression in cancer patients. Neurology, psychiatry and brain research, 17(2), 42-45.
Tokgoz, G. (2008). Prevalence of major depression in patients with cancer and related factors.
Tsunoda, A., Nakao, K., Hiratsuka, K., Yasuda, N., Shibusawa, M., & Kusano, M. (2005). Anxiety, depression and quality of life in colorectal cancer patients. International Journal of Clinical Oncology, 10(6), 411-417.
Van Oers, H. M., & Schlebusch, L. (2013). Anxiety and the patient with breast cancer: a review of current research and practice. South African Family Practice, 55(6), 525-529.
Wardle, J., Robb, K., Vernon, S., & Waller, J. (2015). Screening for prevention and early diagnosis of cancer. American Psychologist, 70(2), 119.
Wong, C. A., & Bramwell, L. (1992). Uncertainty and anxiety after mastectomy for breast cancer. Cancer Nursing, 15(5), 363-371.
Zenger, M., Brix, C., Borowski, J., Stolzenburg, J. U., & Hinz, A. (2010). The impact of optimism on anxiety, depression and quality of life in urogenital cancer patients. Psycho?Oncology, 19(8), 879-886.
In-Text Citation: (Sadoughi, & Salehi, 2017)
To Cite this Article: Sadoughi, M., & Salehi, Z. M. (2017). The Relationship between Anxiety, Depression, and Quality of Life among Women with Breast Cancer. International Journal of Academic Research in Psychology. 4(1), 11-19.