Published June 18, 2018 | Version 0.1
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Lethality datasets for "A comparative study of endoderm differentiation in humans and chimpanzees"

  • 1. University of Chicago

Description

These datasets were used to evaluate the embryonic lethality of 3 categories of genes: genes with shared reduction of variation in gene expression levels, genes with reduction of variation in only one species, and genes without a reduction of variation in either species.To obtain the data, we took the gene list of each of the 3 categories of genes and ran it through the Mammalian Phenotype database from Jackson Lab: http://www.informatics.jax.org/batch/summary in January 2018.

Files

Lethality_non_red_genes.txt

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Additional details

Related works

Is supplement to
10.5281/zenodo.1291650 (DOI)

References

  • Blake JA, Richardson JE, Bult CJ, Kadin JA, Eppig JT, Mouse Genome Database G: MGD: the Mouse Genome Database. Nucleic Acids Res 2003, 31:193-195.
  • Mouse Genome Database (MGD), Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, Maine. World Wide Web (URL: http://www.informatics.jax.org). January 20 2018.
  • Smith CL, Blake JA, Kadin JA, Richardson JE, Bult CJ, the Mouse Genome Database Group. 2018. Mouse Genome Database (MGD)-2018: knowledgebase for the laboratory mouse. Nucleic Acids Res. 2018 Jan. 4;46 (D1): D836–D842.