ORAL DISINTEGRATION TABLETS – AN UPDATED REVIEW

The purpose of writing this review is Oral delivery is currently the gold standard in the pharmaceutical industry where it is regarded as the safest, most convenient and most economical method of drug delivery having the highest patient compliance. It is leads to development of orally disintegrating tablets. This disintegrates in the mouth in seconds without chewing and the need of water which is advantageous mainly for pediatrics, geriatrics and patients having difficulty in swallowing tablets and capsules. The prepared tablets were evaluated for hardness, friability, disintegration time and in vitro drug release ODTs are solid dosage forms containing medicinal substances which disintegrate rapidly, usually in a matter of seconds, when placed on the tongue. The aim of this article is to review the development of ODTs, challenges in formulation, new ODT technologies and evaluation methodologies, suitability of drug candidates, and future prospects. 

Key words: Orally disintegrating tablet, Oral route, Excipients.