Published April 1, 2021 | Version v1
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Preconceptional immunization can modulate offspring intrathymic IL-17-producing γδT cells: possible epigenetic implications mediated by microRNA

  • 1. Laboratory of Medical Investigation LIM-56, Division of Clinical Dermatology, Medical School, University of São Paulo, São Paulo, Brazil

Description

Here, we aimed to evaluate whether maternal OVA-immunization can inhibit the maturation of IL-17-producing gdT cells in mice female offspring thymus and if this mechanism has epigenetic implications mediated by microRNAs (miRNA) expression.

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