Functional Polymorphism in miR-208 Is Associated with Increased Risk for Ischemic Stroke

根据对基因型、模型和等位基因的分析,观察到rs8022522多态性与IS风险之间存在显著相关性(GA与GG:校正OR=2.159,95%CI:1.052-4.430,P = 0. 036;AA 与 GG:调整后 OR = 5.154,95% CI:1.123-23.660,P = 0.035;显性模型:校正OR=1.746,95%CI,1.075-2.838,P = 0.025;G 与 A:调整后 OR = 2.451,95% CI:1.374-4.370)。