Open Access, Peer-reviewed
pISSN 2287-2434
eISSN 2287-447X
    J Korean Oncol Nurs. 2010 Aug;10(2):231-239. Korean.
    Published online Aug 31, 2010.
    https://doi.org/10.5388/jkon.2010.10.2.231
    Copyright © 2010 Korean Oncology Nursing Society
    Original Article

    Characteristics and Quality of Life in Patients with Chemotherapy-Induced Peripheral Neuropathy

    Mi Kyong Kwak,1 Eun Ji Kim,1 Eun Ryung Lee,1 In Gak Kwon,2 and Moon Sook Hwang3
      • 1Oncology Advanced Practice Nurse, Department of Nursing, Samsung Medical Center, Seoul, Korea.
      • 2Professor, Department of Clinical Nursing Science, Sunkyunkwan University School of Medicine, Seoul, Korea.
      • 3Associate Professor, Department of Clinical Nursing Science, Sunkyunkwan University School of Medicine, Seoul, Korea.
    • Address reprint requests to: Kwak, Mi Kyong. Department of Nursing, Samsung Medical Center, 50 Irwon-dong, Gangnam-gu, Seoul 135-710, Korea. Tel: 82-2-3410-2859, Fax: 82-2-3410-2860, Email: mikyong.kawk@samsung.com
    Received June 25, 2010; Accepted August 02, 2010.

    Abstract

    Purpose

    The purpose of study was to identify how patients experienced chemotherapy-induced peripheral neuropathy (CIPN) and quality of life related to CIPN.

    Methods

    This was a descriptive research. We collected data from 105 patients with chemotherapy-induced peripheral neuropathy. They completed a self-reported questionnaire including Eastern Cooperative Oncology Group (EORTC) CIPN20 and items related to their disease and peripheral neuropathy. The investigators filled in part of items about disease and treatment.

    Results

    In the study, duration of peripheral neuropathy was 9.4 month and 54.3% of patients used pharmacological or non-pharmacological interventions. Patients reported the highest score for sensory scale and it's score was 38.74±20.24. The scores for motor scale and autonomic scale were 21.95±19.19 and 26.61±21.0 respectively. This showed that patients more suffered from sensory neuropathy than any other domain of neuropathy. The most frequently selected two items were 'did you have tingling fingers or hands?' and 'did you have tingling toes or feet?'.

    Conclusion

    The results of this study will provide useful information for chemotherapy-induced peripheral neuropathy.

    Keywords
    Chemotherapy; Peripheral neuropathy; Quality of life

    Tables

    Table 1
    Characteristics of the patients (N=105)

    Table 2
    Characteristics related to peripheral neuropathy (N=105)

    Table 3
    Score and frequency per question of EORTC CIPN20

    Table 4
    The differences of CIPN20 by characteristics related to peripheral neuropathy (N=105)

    Table 5
    Correlation between characteristics related to peripheral neuropathy and CIPN20 (N=105)

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    MeSH Terms
    Fingers
    Humans
    Peripheral Nervous System Diseases
    Quality of Life
    Research Personnel
    Surveys and Questionnaires
    Toes
    Metrics
    Share
    Tables
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